Destructive problem of lung elastic tissue/alveoli
symptoms: pink skin due to CO2 retention, purse lipped breathing, dyspnea, orthopnea, barrel chest, use of accessory muscles to breathe
Emphysema
Primarily used as a fast-acting reliever (rescue) drug to be used either during an asthma attack or just before engaging in activity that usually triggers an attack
SABA
albuterol
Autoimmune, idiopathic disease
body does not recognize beta cells as self cells and attacks them; body does not produce any insulin
Type 1 Diabetes
inflammation of the oral cavity
painful, inflamed ulcerations
can be primary or secondary
Stomatitis
most common ulcer
pain usually awakens patient at night
relieved by ingestion of food
duodenal ulcers
inflammation of bronchi & bronchioles; affects only airway, not alveoli
Symptoms: recurrent cough, high sputum production, dusky to cyanotic skin, hypoxia, hypercapnia, digital clubbing, respiratory acidosis
chronic bronchitis
Causes bronchodilation through relaxing bronchiolar smooth muscle by binding to and activating pulmonary beta2 receptors. Onset of action is slow with a long duration. The primary use is prevention of an asthma attack
LABA
-Salmeterol (inhaled drug)
-Indacaterol (COPD only) (inhaled drug)
-Formoterol (COPD only) (inhaled drug)
-Arformoterol
Ranges from insulin resistance with relative insulin deficiency to secretory deficit with insulin resistance
Type 2 Diabetes
interventions for stomatitis
well balanced diet, proper hydration
weekly self exam of mouth
well fitting dentures
swish & spit medications
these drugs decrease gastric acid secretion by blocking histamine receptors in parietal cells
single dose at bedtime
smoking decreases effectiveness
H2 blocker
famotidine (Pepcid)
What is the oxygen therapy goal for COPD
88-92%
Disrupt production pathways of inflammatory mediators. The main purpose is to prevent an asthma attack caused by inflammation or allergies (controller drug)
Corticosteroids
Oral Antidiabetic Drug that inhibits liver glucose production, decreases intestinal absorption of glucose, and increases insulin sensitivity
Cannot be used with contrast agents
Metformin
backward flow of stomach contents into esophagus
overweight/obese patients at high risk
GERD
these drugs totally block the secretion of gastric acid
cannot give with other drugs
long term use can lead to osteoporosis, stomach infections
pantoprazole (Protonix), omeprazole (Prilosec)
NonPharmacological Interventions for COPD
breathing techniques, positioning, effective coughing, exercise, hydration, nutrition (high calorie, high protein), divide activities into smaller parts
Complications of long term corticosteroid therapy
• Diabetes mellitus
• Impaired or decreased immunity
• Fluid and electrolyte imbalances
• Hypertension
• Osteoporosis
• Glaucoma
Complications of Diabetes
Acute: diabetic ketoacidosis, HHS, hypoglycemia
Chronic: cardiovascular disease, cerebrovascular disease, peripheral vascular disease, reduced immunity, retinopathy, neuropathy, nephropathy, sexual dysfunction
Interventions for GERD
Diet: avoid fatty/fried food, caffeine, tobacco, citrus fruits, alcohol, tomatoes, spicy food, peppermint
Lifestyle: avoid triggers, exercise regularly, loose clothing, avoid heavy lifting
Medications: antacids, PPI, H2 blockers
interventions for Gastritis
Medication: H2 blockers, mucosal barrier fortifier, PPI, antacids, treat infection if present
avoid excessive alcohol, caffeine, NSAIDs, corticosteroids
manage stress, smoking cessation
Pharmacological Management for COPD
oxygen therapy
corticosteroids: fluticasone, Beclomethasone
SABA: albuterol, levalbuterol
LABA: Salmeterol, Formoterol
Leukotriene Modifiers: Montelukast
help improve bronchiolar airflow and increase gas exchange by decreasing the inflammatory response of the mucous membranes in the airways. They do not cause bronchodilation
Anti-inflammatories
What are the components of metabolic syndrome
-hyperglycemia
-hypertension
-hyperlipidemia
inflammation of gastric mucosa
can be acute or chronic
caused by long term NSAID use, smoking, alcohol, H. Pylori infection
Gastritis
what are the complications of ulcers
hemorrhage (most serious)
perforation
pyloric obstruction
intractibility