Hypersensitivity
a type I hypersensitive allergic reaction of the skin that is characterized by the sudden appearance of intensely pruritic pink or red discrete papules that progress to wheals of variable size.
What is Urticaria?
illnesses caused by various organisms, some of which usually do not cause disease in people with normal immune systems
What is an opportunistic infection?
The mucocutaneous, musculoskeletal, renal, nervous, cardiovascular, and respiratory systems are most commonly involved with this disorder. Manifestations include joint Swelling, erythematous rashes, behavioral changes, and fatigue are common manifestations of
What is SLE?
These drugs are given to inhibit the inflammatory response to tissue injury and to suppress allergic manifestations.
What are glucocorticoids?
an immune response initiated by T lymphocytes of donor tissue against the recipient’s tissues
What is GVHD (Graft Versus Host Disease)
an allergic reaction that involves the infiltration of fluid in subcutaneous tissue and mucous membranes, resulting in diffuse swelling, which may affect the mucous membranes of the larynx, bronchi, and gastrointestinal tract
What is angioedema?
These receptors are expressed on the surface of T lymphocytes, monocytes, dendritic cells, and mature T cells (T lymphocytes), which are targeted by the HIV virus
What are CD4 receptors?
a rare autoimmune disease affecting the connective tissue of the skin, blood vessel walls, and internal organs.
What is scleroderma?
The first-line agent for RA treatment; also useful in SLE
What is Methotrexate?
abnormally low absolute neutrophil count
What is neutropenia?
caused by antibodies to donor leukocytes that remain in the unit of blood or blood component; it is the most common type of transfusion reaction
What is a febrile nonhemolytic reaction?
This is the amount of virus in the body after the initial immune response subsides and it reflects an equilibrium between HIV levels and the immune response.
What is the viral set point?
Optic neuritis, trigeminal neuralgia, and sensory neuropathy may be present, along with Optic neuritis, trigeminal neuralgia, and sensory neuropathy may be present, and this disorder often manifests in conjunction with other autoimmune diseases, most commonly autoimmune thyroid disease, RA, and SLE
What is Sjogren's Syndrome?
Useful in treatment of RA and SLE, with adverse reactions such as visual changes, GI upset, skin rash, headaches, photosensitivity, bleaching of hair. Patient education includes the need for ophthalmologic examinations (every 6–12 mo).
What are Disease-Modifying Antirheumatic Drugs (DMARDs)?
An ANC (Absolute Neutrophil Count) less than this reflects a severe risk of infection
What is a an ANC less than 500 cells/mm3?
Three defining characteristics include an acute onset of symptoms, two or more of the following symptoms (respiratory compromise, reduced BP, GI distress, and skin or mucosal tissue irritation), and cardiovascular compromise from minutes to hours after exposure to the antigen
What is anaphylaxis or anaphylactic shock?
a malignancy of endothelial cells that line the small blood vessels. Kaposi sarcoma is manifested clinically by lesions of the skin, oral cavity, gastrointestinal tract, and lungs.
What is Kaposi Sarcoma?
Tumor lysis syndrome and acute tubular necrosis are also potential complications of this immune response
What is graft-versus-host disease (GVHD)?
Brain fog, peripheral neuropathy, alopecia, myelosuppression, neutropenia, renal dysfunction, and cardiac toxicity are potential complications and/or adverse reactions for these types of medications.
What is chemotherapy?
An elevation of this whit blood cell _____can be a normal response to increased need (e.g., in acute infection) and is called ______
What are leukocytes and leukocytosis?
This medication, along with continuous IV fluids, is used to treat the medical emergency of Anaphylaxis
What is SQ Epinephrine?
This is the key to treatment
What is adherence to antiretroviral treatment?
Potentially fatal complication that occurs spontaneously or more commonly following radiation, immunotherapy, targeted therapy, or chemotherapy-induced cell destruction of large or rapidly growing cancers such as leukemia, lymphoma, and small cell lung cancer.
What is Tumor Lysis Syndrome?
Patients taking cetirizine, fexofenadine, and loratadine may c/o headache, dry mouth, and fatigue; these are examples of this drug class
What are H1 antihistamine agents?
The ______counts are normally 500 to 1500 cells/mm3 of blood, and when less than 200 signify ________
What are CD4 T-cell count and AIDS?