Bug & Drug
Name 3 drugs that cover anaerobes
What is metronidazole, ampicillin-sulbactam, amoxicillin-clavulanate, piperacillin-tazobactam, moxifloxacin, clindamycin, cefoxitin (2nd generation cephalosporins), meropenem, ertapenem
Recommended treatment duration for SSTIs
What is 5-7 days
Standard regimen for non-severe inpatient CAP. List class(es)
What is a beta-lactam + macrolide or monotherapy respiratory fluoroquinolone
This is the PK parameter we try to achieve when dosing cephalosporins
What is time above MIC (T>MIC) 60-70%
Positive urine cultures with pyuria require treatment with antimicrobials (True of False)
What is false
Name at least 3 beta-lactams that have coverage for Pseudomonas aeruginosa
What is piperacillin-tazobactam, cefepime, ceftazidime, meropenem, imipenem, aztreonam
Answer two questions. What is the recommended treatment duration (range) for:
1. Symptomatic uncomplicated cystitis?
2. Pyelonephritis?
What is 1-5 days (1 for fosfomycin, 3 for FQs and Bactrim, 5 for all others) and 5-7 days (5 for FQs, 7 for all others)
Name the recommended IV treatment option for an ESBL E. coli bacteremia
What is a carbapenem (meropenem)
The AUC:MIC range that vancomycin should be dosed between
What is 400-600
These are risk factors for MRSA/Psuedomonas in CAP, name at least 2
What are recent hospitalization and parenteral antibiotics in the past 90 days, recent MRSA/Pseudomonas isolate in sputum
Name 5 agents (IV/PO) that cover MRSA
What is
IV: vancomycin, daptomycin, ceftaroline, dalbavancin, oritevancin
IV and PO: linezolid, TMP/SMX (bactrim), doxycycline, minocycline, clindamycin
Recommended treatment duration for uncomplicated Gram-negative bacteremia
What is 7 days
This antibiotic is the drug of choice for MSSA bacteremia (name 2)
What Nafcillin or cefazolin
These drugs are at the highest risk for causing CDiff. Name at least 3
What are clindamycin, fluoroquinolones, carbapenems, and 3rd generation (or greater) cephalosporins
Bacteriostatic abx are less effective than bactericidal abx and should be avoided in serious infections (True or false)
What is false
Fluoroquinolones and macrolides can be used for atypical organisms. Name 3 atypicals
What is Chlamydia pneumoniae, Legionella pneumophila, Mycoplasma pneumoniae, Coexiella burnetii
Recommended treatment duration for uncomplicated Staph aureus bacteremia
What is 14 days (2 weeks) + ID Consult!
This antibiotic is the drug of choice for Stenotrophomonas maltophilia
What is TMP/SMX (bactrim)
List at least 3 antibiotics that do not require renal dose adjustments
Ceftriaxone, Oxacillin/Nafcillin, Metronidazole, Moxifloxacin, Azithromycin, Linezolid
List 2 antivirals (Brand and/or generic) used for HIV-PrEP
What are Truvada (Emtricitabine/TDF), Descovy (Emtricitabine/TAF), and Apretude (cabotegravir)
2 Candida spp. are often resistant to fluconazole but typically susceptible to echinocandins. Name at least one
What are Candida krusei and Candida glabrata
Recommended treatment duration for streptococcus pneumoniae meningitis
What is 10-14 days
Recommended treatment regimen for enterococcal endocarditis
What is ampicillin + ceftriaxone (preferred) or ampicillin + gentamicin
Name the laboratory parameter that should be monitored at least weekly for patients on daptomycin
What is CK (creatinine kinase)
List at least 2 AmpC beta-lactamase producing organisms
What are Enterobacter cloacae, Klebsiella aerogenes (formerly Enterobacter aerogenes), and Citrobacter freundii