Miltown
Benzodiazepines
Barbiturates
Xanax and Klonopin
Valium and Librium
100
Miltown's actual name
Meprobamate
100
The larger category benzodiazepines are a part of
Anxiolytics
100
Tolerance happens after...
Two weeks
100
Klonopin is used to treat what kind of disorders?
Seizure disorders
100
First benzodiazepine to be synthesized
Librium
200
Miltown was known as the first minor...
Tranquilizer
200
He played a major role in developing many benzodiazepine drugs
Leo Sternbach
200
Name at least two major negative impacts of using barbiturates
Overdose happens easily, intense withdrawal symptoms, dosage is tricky, no treatment for addiction, highly addictive
200
Chemical formula of Klonopin
C15H10CIN303
200
Which drug's structure is this?
300
True or false: Miltown helps relieve long-term anxiety only
False
300
Explain the mode of action of a benzodiazepine
Benzodiazepines increase the effect of GABA (an agonist) and GABA receptors in the CNS and spinal cord. GABA will attach to a chloride ion channel and allow rapid flow of negative ions into the cell; this makes it more difficult for the threshold to be released and the action potential to occur. The inhibition of action potentials causes many of the benzodiazepine's side effects.
300
Name three symptoms of only barbiturates
Dizziness, headache, abdominal pain, coma, skin rash, hallucinations
300
Chemical formula of Xanax
C17H13CIN4
300
Valium was the highest selling medication in the...
1970s
400
Name at least two of the alternate names Miltown has been marketed as
Amepromat, Quivet, Zirpon
400
Name three symptoms of only benzodiazepines
Memory impairment, appetite changes, constipation, weight gain, dry mouth, fatigue, jaundice, seizures, and/or changes in heart rate
400
Barbiturates inhibit which part of the body?
CNS
400
Xanax was the first drug to be approved for...
Panic attacks
400
Parts of the brain that librium and valium affect
The limbic system
500
Miltown became particularly popular in this part of the US at first
Hollywood
500
Neurotransmitter that benzodiazepines enhance the effect of
GABA
500
True or false: barbiturates are still in use
False
500
Which drug's structure is this?
500
Explain how a certain impacted part of the brain connects to one of the symptoms of valium and/or librium usage
Hypothalamus --> visceral activities impaired after serious usage
Spinal chord --> inhibition of motor pathways causes a muscle-relaxant effect
Amygdala --> weaker emotions
Thalamus and reticular formation --> these drugs are sedatives (they trigger sleepiness)