Antibiotics
Antivirals
Antifungals
Anti-Inflammatories
NCLEX Scenarios
100

A patient taking gentamicin should be monitored for which toxicities?

Ototoxicity and nephrotoxicity

100

What is the MOA of acyclovir?

Inhibits viral DNA synthesis

100

What is a serious cardiac side effect of fluconazole?

QT prolongation and torsades de pointes

100

What is the primary risk of aspirin in children with viral infections?

Reye’s syndrome

100

A patient taking tetracycline is prescribed calcium supplements. What is the priority?

Hold calcium; it interferes with tetracycline absorption

200

Which class of antibiotics can cause Achilles tendon rupture?

Fluoroquinolones

200

Which antiviral is used for Influenza A prophylaxis and can cause seizures?

Rimantadine

200

What nursing teaching is essential for clotrimazole use?

Do not use in systemic candidiasis; monitor liver function

200

Which anti-inflammatory has no significant GI toxicity?

Acetaminophen

200

A patient on sulfonamides develops a widespread skin rash. What should the nurse do?

Stop the medication and notify the provider—possible Stevens-Johnson Syndrome

300

Which antibiotic class is contraindicated with calcium and causes teeth staining?

Tetracyclines

300

Which antiviral requires cautious use in renal impairment and can cause phlebitis?

Acyclovir

300

Which antifungal can cause Stevens-Johnson Syndrome and hepatotoxicity?

Fluconazole

300

Which NSAID can cause fluid retention and increased risk of MI?

Ibuprofen

300

A nurse is administering vancomycin. What is the best action to prevent adverse effects?

Infuse over at least 60 minutes

400

A nurse is educating a patient on sulfonamides. Which teaching is correct?

Drink 2L of water daily to prevent kidney stones

400

What should a nurse monitor in a patient taking oseltamivir?

Seizures and renal function

400

Fluconazole is contraindicated with which types of medications?

QT-prolonging drugs like erythromycin and quinidine

400

A patient on ketorolac complains of black stools. What should the nurse suspect?

GI bleeding

400

A patient reports dark urine and fatigue after starting metronidazole. What should the nurse do?

Evaluate for hepatotoxicity

500

Vancomycin must be infused slowly to prevent which reaction?

Red man syndrome

500

Which antiviral requires dose adjustments based on weight in obese patients?

Acyclovir

500

What are common GI effects of antifungals?

Nausea, vomiting, elevated LFTs

500

What lab should be closely monitored for a patient on high-dose acetaminophen?

Liver function tests (AST/ALT)

500

A patient prescribed oseltamivir has had flu symptoms for 3 days. What is the nurse’s best action?

Withhold the drug; it's effective only within 48 hours of symptom onset