Warfarin
Nutrition
Procedures
LMWH
DOACs
100

The standardized blood test used to measure activity of clotting factors affected by warfarin.

What is INR (international normalized ratio)?

100

The vitamin that clotting factors are dependent on and which the warfarin interferes with.

What is Vitamin K?

100

A commonly used low molecular weight heparin used for bridging anticoagulation when patients need to hold warfarin for procedures with higher bleeding risk.

What is enoxaparin (Lovenox)?

100
The period of time after a procedure that LMWH could be restarted.
What is ~36-48 hours?
100

These are the advantages of DOACs over traditional warfarin treatment.

What are: No required lab monitoring, less drug interactions, less food interactions, less complicated dosing?

200
This cardiac condition is the most common indication for warfarin.
What is atrial fibrillation?
200

These are foods that can significantly interfere with the effects of warfarin due to their high vitamin K content.

What is spinach, kale, collard greens, brussel sprouts, broccoli?

200
These are factors that should be considered when deciding on whether a patient needs to be bridged for a procedure.
What are thromboembolic risk, type of procedure, bleeding risk of procedure, renal function?
200
The proper site for injection of enoxaparin (Lovenox)?
What is the abdomen?
200
Besides bleeding, the most common side effect of dabigatran.
What is GI adverse events (dyspepsia, GI hemorrhage, nausea)?
300
The duration of time warfarin should be held for procedures that are of higher bleeding risk.
What is 5 days?
300

This food product is a CYP 3A4 inhibitor that can raise drug levels of multiple CYP 3A4 substrates including apixaban.

What is grapefruit juice?

300
The duration of time the newer DOAC agents should be held prior to procedures with higher bleeding risk.
What is 1-2 days? (up to 3-4 days for Pradaxa if poorer kidney function)
300
The amount of time patients should hold enoxaparin prior to procedures.
What is 24-36 hours?
300
This DOAC agent has special storage precautions: it should remain in original contain to avoid moisture damage. After being opened, it is good for 120 days.
What is dabigatran (Pradaxa)?
400
This condition can clear vitamin K producing bacteria from the GI and cause elevated INR.
What is diarrhea (or bowel cleansing)?
400

These are foods that can potentiate the effects of warfarin and potentially increase bleeding risk.

What is pomegranate and cranberry?

400
The amount of time elapsed after a procedure, when patient can restart anticoagulant.
What is same day (warfarin) or next day (LMWH, DOACs)?
400
These are factors that need to be considered when dosing enoxaparin (Lovenox).
What is body weight and kidney function?
400
This DOAC agent may be desirable for some because it is dosed just once daily.
What is rivaroxaban (Xarelto)?
500
This bad habit can interact with warfarin by inducing its metabolism, causing low INRs.
What is cigarette smoking?
500
This beverage is not recommended for patients on blood thinners, due to increased GI bleeding risk.
What is alcohol?
500
The providers who should be contacted about recommendations on holding DOACs for procedures.
Who are primary care providers (PCPs)?
500
This is the preferred LMWH to be used in treatment of DVT/PT in oncology patients.
What is dalteparin (Fragmin)?
500
These are the DOAC agents that have restrictions with impaired renal function.
What are dabigatran, rivaroxaban, and apixaban?