Textbook Knowledge
The textbook defines this disorder by symptoms such as hallucinations, delusions, disorganized thinking, and social withdrawal
Schizophrenia
Aripiprazole maintenance unexpectedly caused this outcome in participants
Increased cocaine self-administration
This research focuses primarily on the treatment of dependence on this substance
Alcohol
Symptoms like flat affect, lack of motivation, and social withdrawal are referred to as this category of schizophrenia symptoms
Negative symptoms
Aripiprazole is a long-acting atypical antipsychotic with an approximate half-life of this many hours in humans
75 hours
Participants consumed a “priming drink” then had free-choice consumption of up to eight drinks in exchange for this type of alternative reward
Bar credit
Most antipsychotics block this receptor type, which is thought to be over-active in schizophrenia
Dopamine D2 receptors
DOUBLE JEOPARDY !!!!
What are 2 reasons data was used from only 8 participants
- 3 exceeded cardiovascular criteria
- 1 was arrested
- 1 was participating in another research study
- 13 failed to reliably make their appointments
The study found a significant reduction in drinking in the lab among individuals with this trait
Low self-control
or
High impulsivity
Aripiprazole, risperidone, and olanzapine are examples of this newer class of antipsychotics with a weak affinity to the D2 receptor
Atypical antipsychotics
What was the researchers’ main conclusion about aripiprazole’s clinical potential for cocaine dependence
Aripiprazole is not a useful or effective treatment for cocaine dependence
The study suggests that medications that target this type of neurotransmission might benefit drinkers with low self-control
Cortical dopamine/serotonin balance