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Schizophrenia
First Generation Antipsychotics
Second Generation Antipsychotics
Third Generation Antipsychotics and Future Developmental Efforts
Other Disorders
100
This is the theory that schizophrenia developed from a dysfunction in the dopamine pathways of the brain.
What is the dopamine theory?
100
This is another name for first generation antipsychotics.
What are Typical Antipsychotics?
100
This is the major side effect of clozapine which results in the loss of white blood cells.
What is agranulocytosis?
100
This is the medical equivalent name to Blonanserine.
What is Lonasen?
100
These are the names of 4 of the 8 disorders listed for other applications of SGAs.
What are Bipolar Disorder, Unipolar Depression, Dementia, Autism Spectrum Disorders (ASD)(and Pervasive Developmental Disorder, Agitation and Aggression), Post-traumatic Stress Disorder (PTSD), Obsessive-Compulsive Disorder (OCD), Borderline Personality Disorder (BPD) and/or Parkinson’s Disease?
200
These are the three general types of symptoms schizophrenic individuals experience.
What are positive, negative and cognitive symptoms?
200
The blockage of D2 receptors in the basal ganglia from FGAs can lead to this acute extrapyramidal side effect characterized by a "tremor at rest."
What is neuroleptic-induced parkinsonism?
200
This SGA is as effective as haloperidol in reducing positive symptoms of schizophrenia but does not produce high EPS.
What is risperidone (risperdal)?
200
This drug is used in Japan and Korea but is in clinical trials in the United States.
What is Blonanserin(e)?
200
These are the names of 3 of the 5 more commonly used SGAs to treat other psychological disorders.
What are risperidone, olanzapine, aripiprazole, quetiapine and/or ziprasidone?
300
This phase of schizophrenia can be classified by subtle motor, cognitive and social impairments.
What is premorbid phase?
300
This was the first therapeutic alternative to phenothiazines introduced in 1967.
What is haloperidol?
300
This is the concerning type of EKG prolongation that occurs in people taking SGAs.
What is QT prolongation?
300
BL-1020 is an example of this type of agent in clinical trials that produces little EPS and can prevent or improve cognition in treating schizophrenia.
What are GABAergic agents?
300
75% of the population of patients with this disorder are female.
What is Borderline Personality Disorder (BPD)?
400
These are 3 of the 6 negative symptoms associated with schizophrenia.
What are absence of normal qualities, blunted emotional expression, speech impediment (alogia), decreased motivation and interest (avolition), lack of ability to experience pleasure (anhedonia) and/or social withdrawal and isolation?
400
This FGA has been reported to block monoamine oxidase (MAO) which causes symptoms of euphoria.
What is molindone (moban)?
400
This enzyme is stimulated by SGAs and may attribute to weight gain.
What is hypothalamic AMP-activated protein kinase. (AMPK)?
400
This drug in clinical testing prefers D3 over D2 could treat schizophrenia and mania at high doses and depression at low doses with few metabolic problems.
What is Cariprazine?
400
An increased release of this hormone has raised concerns about the long-term safety of risperidone in children with Autism Spectrum Disorder.
What is prolactin?
500
This is the receptor that may be responsible for the benefits of antipsychotics.
What is the 5-HT2 receptor?
500
This FGA is used to treat motor and phonic tics in patients with Tourette's disorder in the United States.
What is pimozide (orap)?
500
This EKG abnormality is a type of polymorphic ventricular tachycardia that twists the QRS complex.
What is torsades de pointes?
500
This supplement found in fish may offer a safe way to reduce the rate of progression in psychotics disorders in adolescents and young adults.
What are omega-3 polyunsaturated fatty acids (omega-3-PUFA)?
500
This drug to treat dementia as well as bipolar patients received a "black box" warning from the FDA because of the increased risk of strokes, heart attacks and infections.
What is Symbyax?