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100
Simeprovir (Olysio) is a protease inhibitor that was approved in 2013. for the treatment of what disease? Patients of eastern ________________ ancestry exhibit more adverse effects to this drug than other groups. This drug is used to treat _____________________.
Eastern Asian & hepatitis C Page 648
100
What drug would be appropriate to treat cytomegalovirus (CMV) retinitis?
ganciclovir (Cytovene) Page 647 ***The ophthalmic form (Vitrasert) must be surgically inserted.
100
This non-HIV medication is contraindicated for pregnant women and their male partners due to teratogenic properties.
ribavirin (Virazole) Page 655
100
What drugs are recommended for use in an occupational HIV exposure?
emtricitabine and tenofovir Page 659
100
Every person that has AIDS has _______________.
HIV----but not every person that has HIV has AIDs Read Pages 649-651
200
What is the major dose-limiting adverse effect of zidovudine (Retrovir)?
Bone marrow suppression Page 654
200
This drug is given to HIV-infected pregnant women to prevent maternal transmission of the virus to the infant.
Zidovudine (Retrovir) Page 654
200
This combination (cocktail) of antiretroviral drugs is started immediately after the diagnosis of HIV is made.
Highly active antiretroviral therapy (HAART) Page 651
200
This HIV drug is given to HIV-infected pregnant women and to newborns to prevent maternal transmission of the virus to the infant.
Zidovudine (AZT) Page 654
200
Clients taking antiviral medications should be encouraged to drink how much fluid per day unless medically contraindicated?
Up to 3000 mL/day Page 658
300
When should drugs such as oseltamivir (Tamiflu) or zanamivir (Relenza) should be started?
Within two days of the onset of flu symptoms Page 648
300
Due to a short half-life, acyclovir (Zovirax) should be administered _______________ times a day if given orally and _________________ times daily if given IV.
5 times daily orally & 3 times daily IV Page 647
300
What is considered the “breakthrough” drug for chronic hepatitis C?
sofobuvir ((Solvald). Page 648
300
What is an immunoglobulin?
A glycoprotein produced and used by the humoral immune system to attack and kill any substance (antigen) that is foreign to the body. Page 642
300
23. The varicella-zoster virus commonly causes this illness during childhood and another illness later in life. What are the illnesses?
Chicken pox in childhood and shingles in late adulthood Page 644
400
What is the side effects of topical acyclovir (Zovirax) that is different than the oral form?
Burning when applied Page 646
400
A patient taking acyclovir (Zovirax) for herpes knows it will dry & crust over _____________________.
Lesions Page 659 ***** It will not eradicate the herpes virus nor does it protect others from getting the virus. Teach to abstain from sexual intercourse during outbreaks.
400
A major adverse effect of protease inhibitors is?
Lipid abnormalities that redistribute fat stores under the skin that leads to undesirable cosmetic outcomes for the client. Page 655
400
The aerosol form of this drug used for respiratory syncytial virus (RSV) must not be used by or around pregnant women.
ribavirin (Virazole) Page 648
400
Which group of people has a rate of HIV infection that is seven times higher than in white Americans?
African-Americans Page 649
500
This drug is indicated for chronic hepatitis B. It is excreted by the kidneys and dose adjustments may be required in clients with renal dysfunction.
telbivudine (Tyzeka) Page 649
500
Name three types of herpes infections.
Genital herpes, chickenpox, shingles, mononucleosis Page 644
500
If a client is taking HAART drugs and is also taking other medications. What should the nurse do relating to these medications?
The nurse needs to check that there are no drug interactions. The client should bring in the other medications so the nurse can check them against the HAART therapy. Many of the HIV drugs are involved in interactions and may necessitate alternate therapy. *****HAART must be taken as prescribed. Their ability to fight the virus depends on adequate dosing. No current drug kills HIV. Page 653
500
Are there any contraindications for HIV medications?
Usually the only contraindications are a known severe drug allergy or an intolerable toxicity. This is because HIV is always fatal if left untreated. Other medications may have to be managed but the HAART medications are the lifesaving factor. Page 652
500
This HIV drug is associated with the breakdown of muscle cells. The nurse should assess skeletal muscle functioning and pain levels for patient safety.
Raltegravir (Isentress) Page 655