ELN
Complete the following sentence:
" Helps to keep track of who did what,_____ and why"
When
What does "SOP" stand for?
Standard Operating Procedures
Complete the following sentence:
"It is a ________ for laboratory-related data and automates many of the manual and time-consuming tasks involved in sample tracking, processing, analysis, and reporting"
Central repository
Chromatography is the technique for the separation, purification, and "_____" of compounds.
Testing.
Acts as a "______" document management system, collecting, cataloging, and storing data generated by and in a scientific lab.
Centralized
Mention an example of "Collection" according to the presentation of ELN.
Folder
Notebook
Experiment
User, etc.
Explain one main function of LES.
-Manage the execution of lab methods and standard operating procedures.
-Guide the proper execution of procedures and standard operating procedures.
- Manage method/procedure versioning.
- Allow use of calibrated systems only.
Mention and describe three benefits of the LIMS
1. Increased efficiency and productivity
LIMS systems automate many of the manual and time-consuming tasks involved in laboratory workflows, reducing errors, minimizing turnaround times, and increasing overall efficiency and productivity.
2. Enhanced regulatory compliance
LIMS systems help laboratories comply with regulatory requirements and guidelines, including those related to data privacy, data security, and quality management systems, reducing the risk of non-compliance penalties and fines.
3. Cost Savings
LIMS systems help laboratories save costs by reducing the need for manual data entry and processing, minimizing errors and rework, and improving overall efficiency and productivity, leading to better resource utilization and cost savings.
Name at least two chromatography types:
Adsorption Chromatography
Thin Layer Chromatography
Partition Chromatography
Size Exclusion Chromatography
Ion Exchange Chromatography
Chiral Chromatography
Reverse Phase Chromatography
Gas Chromatography
Is it true that SDMS is designed to handle unstructured data?
True. This is designed to handle data from LIMS or ELN
ELNSs are usually divided into 3 Tiers. Which are they?
Database, Application Server and Client
What is a Lab Method?
A Lab Method is a configuration of steps and data collection involved in a lab execution.
Describe the different roles of an Astrix consultant when working on a LIMS project
Explain four functionalities of a CDS.
- Manage instruments, system suitability tests, acquisition and processing of the chromatograms.
- Reporting tools: Interpret data from chromatography instruments and convert it into a human-readable format.
- Back up: Record data for gas, liquid, ion, and supercritical fluid analytic chromatography instruments, which is accessible over the internet.
- Automated and Customized Calculations
Mention at least two SDMS utilized in Astrix.
-Thermo Fisher Sample Manager.
- Agilent. Open Lab.
-ACD/Labs.
-Logilab/ SDMS.
-NuGenesis
Which status of ELN is equal to " Close the experiment"?
*According to the ELN presentation*
Signed
Name four lab procedures that could benefit when using an LES.
1.Glassware preparation
2.Reactants preparation
3.Sample preparation
4.Analytical procedure
Explain the difference between these types of LIMS:
-Open Source LIMS.
-Industry-specific LIMS.
Industry-specific LIMS: Systems are tailored to meet the specific needs of particuInternetlar industries, such as healthcare, environmental testing, or pharmaceuticals. These systems offer specialized functionalities and features that are specific to the industry.
Open-source LIMS: Systems are developed by a community of developers and are available to users free of charge. These systems offer flexibility and customizability, enabling users to modify and add functionalities as needed.
What term refers to the infrastructure that allows multiple users to access and run applications on remote servers, providing a virtualized desktop environment?
Networked CDS-Citrix
What does the acronym of ALCOA mean?
A: Attributable.
L: Legible.
C: Contemporaneously Recorded.
O: Original.
A: Accurate
Explain the difference between Countersigned and Second Science Review.
*According to the ELN presentation*
Countersigned: The second person that reviews the experiment and gives approval. Nor validate quality nor provide feedback.
Second scientist review: This person reviews the entire experiment, from top to bottom to provide feedback.
Mention at least 5 benefits LES brings to a lab.
Explain a generic sample flow in a LIMS. Describe three main functions of this system.
Flow:
Receive the sample > Perform Data Entry > Review the sample > Dispose the sample
Sample Management:
Tracking and managing samples: A LIMS system allows laboratory personnel to track samples from receipt to disposal, including their location, testing status, and associated data.
Specimen labeling and storage: The system automates sample labeling, tracking, and storage to ensure proper identification and management of samples.
Sample tracking and tracking history: A LIMS system maintains a detailed tracking history of all samples, including their processing steps, storage, and testing history.
Data management and organization: The system organizes and manages all data related to the samples, including test results, reports, and associated documentation.
Workflow management:
Streamlining laboratory workflows: LIMS systems streamline laboratory workflows by automating many of the manual tasks involved in sample processing, analysis, and reporting.
Automating sample processing: The system automates sample processing steps, including sample receipt, preparation, testing, and reporting.
Managing schedules and deadlines: The system manages schedules and deadlines associated with laboratory testing and reporting, ensuring that all tasks are completed on time.
Assigning tasks to lab personnel: LIMS systems allow for the assignment and tracking of laboratory tasks and responsibilities to specific lab personnel.
Quality Control and assurance:
Ensuring compliance with standards and regulations: LIMS systems ensure that laboratory testing and reporting comply with relevant standards and regulations.
Quality control of data: The system provides quality control checks for all data associated with samples, including test results and reports.
Sample tracking: LIMS systems track all samples and associated data, ensuring that they are processed, stored, and disposed of correctly.
Data management and reporting: The system manages and reports on all laboratory data, including test results, reports, and associated documentation, ensuring that they are accurate, complete, and easily accessible.
What is the MAIN advantage of having a Data Acquisition server (e.g. Waters LAC/E or Agilent AIC)
Data Buffering
Describe and explain the data transfer process performed by an SDMS.
- Capture file.
- Extract Data.
- Use data.
- Store files.
- Search data.
- Reuse data.