Single-Use
This component secures tubing onto hose barb fittings.
What are retainers or fasteners?
No delamination or additives to create a low extractable profile are the results of this aspect of Aramus
What is single layer film/technology?
The most widely used storage container for Freeze/thaw and low temperature processing.
What are bottles?
The most common coolant used in shipping, holding temperatures down to -80 C
What is dry ice?
The conduction based equipment/method to consistent and scalable freeze bags.
What is plate freezing?
AQG connections and tube welding are examples of this.
What are aseptic/sterile connections?
The number of ports/tube lines supported by the 5L bag.
What are 3 ports?
Name of one company that also make fluoropolymer single-use bags.
Who is Saint-Gobain or W.G. Gore?
The temperature(s) below which cell activity stops to allow for stable frozen storage in HDCB and Cryopreservation
What is -135 to -150C?
A challenge of the freeze process where the formulation distribution is non-homogenous (can be seen using dye)
What is cryoconcentration?
SUT eliminates the need of _____ vs. Stainless Steel because each item is only being used once.
What is cleaning validation?
The secondary containers for bags Entegris offers.
What are shells and cassettes?
Company that produces both bottles and bags which can be used for freeze/thaw applications.
The amount/percentage that fluid expands when frozen.
What is about ~10%?
On most bag assemblies, this component is most fragile and likely to break in low temperature applications
What is the tubing?
The number of bacteria living on a surface that has not been sterilized.
What is bioburden?
The temperature region below which a materials behavior changes from rubber-elastic to a glassy-brittle state.
What is Glass Transition Temperature(Tg)?
Three types of storage containers used for low temperature bulk drug storage
What are bottles, bags, and SS containers?
An added solution used to improve cell survival during freezing in HDCB and Cryopreservation
What is a cryoprotectant (e.g. DMSO)?
Recently launched capability to develop custom Aramus bag geometries.
What is flexible geometry or shaped Aramus?
Chemicals/compounds found in SUT systems that can contaminate the final product.
What are extractables and leachables?
The smallest and largest bag sizes of standard Aramus bags currently available
What are the 20mL and 20L sizes?
Competitor offering an end-to-end solution but without using conventional bag or bottle containers.
Who is Meissner?
Most common method of thawing frozen containers, especially smaller bags and vials.
What is a water bath?
Entegris' largest client using bags for vaccine manufacturing
Who is Moderna?