IBD pathophysiology
This Irritable Bowel Condition has smoking cessation as an exacerbating factor
What is Ulcerative Colitis?
This drug therapy class functions by inhibiting pro-inflammatory cytokines
What are glucocorticoids?
Patients using this IBD therapy should be getting yearly eye exams because of the risk of cataracts disease.
What is corticosteroids?
This antihistamine should not be taken with food because food will decrease its effectiveness.
What is Fexofenadine (Allegra)?
This medication is the first line therapy for a patient with upper airway cough syndrome.
What is inhaled ipratropium?
This irritable bowel disease condition can show fistulas, fissures, cobblestoning and fat wrapping after imaging is done.
What is Crohn's Disease
This specific drug is a second-generation selective Janus kinase inhibitor specifically targeting JAK1.
What is Upadacitinib?
Patients using these IBD therapies should watch out for the box warning of lymphoma and should get genetic testing for TPMT.
What is Azathiopurine and 6-MP?
This antihistamine has a box warning for potential neuropsychiatric effects
What are leukotriene receptor antagonists (Montelukast/Singulair)?
This medication should be used for a patient with a cough caused by upper airway cough syndrome.
What is a 1st generation antihistamine + decongestant?
This IBD condition has loose, bloody stools as a symptom.
What is Ulcerative Colitis?
This drug is a selective sphingosine-1-phosphate (S1P) receptor modulator targeting S1PR1, S1PR4, and S1RP5.
What is Etrasimod (Velsipity)?
This drug is used only for severe ulcerative colitis that has failed to respond adequately to glucocorticoid therapy.
What is Cyclosporine?
These two intranasal corticosteroids have the lowest bioavailability and therefore often preferred.
What are mometasone and fluticasone?
What is gabapentin?
This is the severity classification for a Crohn's disease with a fever, weight loss, abdominal pain, and significant anemia.
This drug functions as an anti-folate and interferes with the inflammatory actions of interleukin-1, stimulates release of adenosine, and stimulates apoptosis of T lymphocytes. It is also recommended to be supplemented with folate to reduce the risk of side effects.
What is methotrexate?
Patients using this IBD therapy that functions as a Janus Kinase inhibtior should be cautious of the increased risk for herpes zoster infection and other infections (TB, bacterial, viral, fungal).
What is Tofacitinib?
This drug class is the most effective for all symptoms of allergic rhinitis.
What are intranasal corticosteroids?
This cough classification of a patient with a cough for 4 weeks and secretions present but difficult to expel.
What is ineffective sub-acute cough?
These are the 4 areas of the body that can have extra-intestinal manifestations from IBD.
What are the joints, eyes, skin, and liver?
This drug is a humanized monoclonal antibody targeted against the a4B7 integrin subunit resulting in gut-selective anti-inflammatory activity.
What is Vedolizumab (Entyvio)?
Patients using this drug class to treat their IBD are at a greater risk of TB.
What are anti-TNF agents? (Infliximab, Adalimumab, Certolizumab, etc)
This drug class can have ADRs such as drowsiness, dry mouth, urinary retention, and constipation but is the preferred drug for intermittent symptoms of allergic rhinits.
What are intranasal antihistamines?
This medication functions by increasing secretions and reducing viscosity of mucus and is often used for a productive cough.
What is Guainfenesen?