Autoantibodies
Clinical
Diagnostic
Treatment
Common systemic Manifestations
100

Positive RF, ANA, SCL-70 with a positive tent test

What is Scleroderma?

100

Pt has rash along cheeks and nose that spares nasolabial folds 

(BE SPECIFIC)

What is acute cutaneous Lupus?

100

Pt has positive biopsy of salivary gland with lymphocyte infiltration can we make a diagnosis?

Yes this is Sjogren's

100

What is the first line treatment for a lupus flare?

What are low dose corticosteroids?

100

Pt has 2 fingers affected that turn white in the cold which form of Raynaud's is this?

This is primary Raynaud's and it is unassociated from Autoimmune diseases

200

Positive RF, ANA, SSA, SSB 

positive Schirmer Test

What is Sjogren's? 

200

Calcinoses of the fingers with GI dysfunction and Raynaud's 

What is Scoleraderma?

200

Pt has had recent biopsy of kidney which came back positive for SLE class III is this enough for complete diagnosis

Yes


200

What is used to prevent renal crisis in Scleroderma? 

What are ACE inhibitors?

200

What is the common systemic heart manifestation?

What is pericarditis (flask appearance)?

300

Complement in low (C3, C4), low platelets, with positive DsDNA

What is Lupus?

300

Pt has shoulder pain (unilateral shoulder bursitis) with prolonged morning stiffness and fatigue 

What is polymyalgia Rheumatica?

300

Pt is on isoniazid with a positive ANA and joint pain is this a enough for a lupus diagnosis?

NO you would need to test for AntiDsDNA

300

Pt is unresponsive to TNF-a inhibitors with a high CRP what is the next line treatment?

What are Il-6 inhibitors?

300

Pt has less pain after activity what is this called

What is the gelling pneomenon?
400

Positive RF, ANA, CCP 


Rheumatoid Arthritis

400

Pt has foot drop with seizures and scarring alopecia 

What is Chronic Discoid Lupus (systemic)?

400

Pt has joint aspiration with WBC > 10,000 but a negative RF what is the next test to order?

What is a antiCCP?


400

What is not responsive to corticosteroids when pt is having joint pain in the knees symmetrically?

What is Osteoarthritis?

400

The most common joints associated with inflammatory arthritis

What are the wrist and MCP?
500

Elevated CRP, ESR

Negative ANA

Negative RF

Low blood count 

What is Polymyalgia Rheumatic? 

500

Pt presents with splenomegaly, reactive arthritis, neutropenia and has a leg ulceration

What is Rheumatoid arthritis?

500

How many points are needed on the Scleroderma scale for a diagnosis?

What is 9 points?

500

What is the necessary long term treatment of lupus?

What is Hydroxychloroquine?

500

Pt has lung X-ray and it is described as honey comb appearance 

What is Interstistial Lung Disease?