Values
Antidotes
Drug class / name
CBC values
disease sx
100

ACT 

Normal 70-120

Therapeutic >300

100

Warafin

Vit K
100
Vit K antagonists 

Warfarin/ comadin 

Take @ same time each day 


100

RBC

Men 4.5-6

women : 4-5 

100

PAD

dependent rubor 

Elevation pallor 

Intermittent Claudication

Parasthesia 

Decreased/absent pulses 

Thin shiny taught hairless skin 

Ulcer & ischemia : ulcers on toes and lower extremities (lateral Malleolus) 

——> light pink or Eschar with punched out appearance & minimal drainage 

200

PTT

Normal 30-40s 

Therapeutic 46-70s

200

enoxaparin 

Protamine

200

Low molecular weight heparin 

Deltaparin & enoxaparin 

SQ 

Routine coag. Tests not required 

Monitor cbc

DONT EXPEL AIR BUBBLE

200

WBC

5-10k

200

PVD

swelling edema

Pain that’s throbbing / aching 

Pain upon dependence & relief on elevation 

Brown bronzing skin 

Bounding pulses & warm skin 

ulcer : medial malleolus, irregular borders, lots of drainage painful, dark red granular tissue 


300

Warafin

Norm :0.75-1.25

Therapeutic: 2-3

300

Heparin sodium

Protamine @ regular intervals 

300

Heparin sodium 

heparin sodium 

IV or SQ 

Monitor PTT & ACT to find therapeutic range 



300

Playlets 

150k-400k

400

Low molecular weight heparin: enoxaparin

Therapeutic : 1.5units/ml

400

Factor Xa inhibitors

Andexanet alfa 

400

Factor XA inhibitors 

End in XABAN aside from SQ fondaparinux 

LEAVE air bubble 

Routine coag. Not needed monitor CBC

MAY CAUSE THROMBOCYTOPENIA 

400

Hgb

Men 14-18

Women 12-16

500

Heparin sodium

Act therapeutic :>300

Ptt therapeutic: 46-70s

500

VKA bleeding 

IV vit K w frozen plasma 

500

Guess what number 

3

500

Hct

Men:45-55

Women:37-47