It's easy as 1,2,3 (math)
To be or not to be (english)
4 score and 7 years ago... (history)
How things are made (science)
Sights and Sounds (art/music)
100

The lowest prime number

What is 2?

100

The author of "The Great Gatsby"

Who is F. Scott Fitzgerald

100

The era that marked the switch from agriculture to industry 

What is the Industrial Revolution?

100

The closest planet to the sun

What is mercury? 

100

The famous artist who cut off his own ear 

Who is Vincent Van Gogh?

200

The day Pi Day is celebrated

What is March 14 (3.14)
200

The name of the lion in "The Lion the Witch and the Wardrobe"

What is Aslan?

200

This French queen was executed during the French Revolution

Who was Marie Antoinette? 

200

Known as the "powerhouse of the cell"

What is the mitochondria?

200

The person who Kendrick Lamar's "Not Like Us" is about

Who is Drake?

300

The original name for the number zero

What is cipher?

300

One of the following is NOT a type of poem: sonnet, haiku, ballad, simile

What is a simile?

300

The youngest Nobel Peace Prize winner (won at age 17 in 2014)

Who is Malala Yousafzai?

300

The rarest blood type

What is AB negative? 

300

The painter of the ceiling of the Sistine Chapel 

Who is Michelangelo? 

400

These can be mixed, complex, and/or vulgar

What are fractions?

400

The term for a word/phrase that means the opposite of its literal meaning

What is an oxymoron?

400

The name of the international group formed to maintain peace after WWI

What is the League of Nations?

400

The psychological concept Pavlov's dog helped him describe 

What is conditioning?

400

The movie musical that starred Diana Ross and Michael Jackson

What is "The Wiz"?

500

This unit of time is 1/100th of a second

What is a jiffy?

500

The name of this symbol: &

What is an Ampersand?

500

She was known as "the maid of Orleans"

Who is Joan of Arc?

500

What a Geiger Counter measures 

What is radiation?

500

The instrument that Louis Armstrong played 

What is trumpet?