Microorganisms & Mechanisms
Bacteria, Viruses, Fungi & Parasites
Immune Deficiency & Autoimmunity
Sepsis & Bacteremia
Meningitis & CNS Infections
100

This term describes organisms whose cells have a true nucleus and membrane-bound organelles.

Answer: What are eukaryotes / eukaryotic organisms?

100

This gram-positive coccus is a common cause of skin and soft tissue infections. 

Answer: What is Staphylococcus aureus?

100

This term describes when part of the immune system is not working properly, making a person more likely to get infections.

Answer: What is immune deficiency?

100

This term means that bacteria are present in the bloodstream.

Answer: What is bacteremia?

100

This term describes inflammation of the membranes that cover the brain and spinal cord.

Answer: What is meningitis?

200

According to Table 8.1, these two broad classes of microorganisms are not cellular: they contain genetic material but no cellular structure.

Answer: What are viruses and prions?

200

This virus as a cause of chickenpox and shingles.

Answer: What is varicella-zoster virus (VZV)?

200

These immune deficiencies are present at birth and caused by a problem in the genes (Table 8.10).

Answer: What are primary (congenital) immune deficiencies?

200

This is a life‑threatening condition where the body’s response to infection damages its own tissues and organs

Answer: What is sepsis?

200

Name two classic signs/symptoms in the initial clinical presentation of acute bacterial meningitis.
Answer (any two):


  • What are fever and severe headache?
  • What is nuchal rigidity (stiff neck)?
  • What is photophobia (sensitivity to light)?
  • What is nausea and vomiting?
  • What is confusion or decreased level of consciousness?
300

From Table 8.3, this is the term for a structural change in antigens that helps pathogens escape immune detection, commonly seen in influenza viruses.

Answer: What is an antigenic shift?

300

Fungi that form multicellular, filamentous structures are described by this term.

Answer: What are moulds?

300

In this type of disorder, the immune system mistakenly attacks the body’s own cells as if they were foreign.

Answer: What is an autoimmune disease?

300

Name two common early clinical signs that might make you suspect sepsis in a hospitalized patient.
Answer (any two):


  • What are fever or hypothermia?
  • What is tachycardia (increased heart rate)?
  • What is tachypnea (increased respiratory rate)?
  • What is hypotension (low blood pressure)?
  • What is new confusion or decreased level of consciousness?
300

Compared with viral meningitis, bacterial meningitis is more serious. List two expected CSF findings in bacterial meningitis.
Answer (any two):


  • What is increased protein?
  • What is decreased glucose?
  • What is high white blood cell count (mainly neutrophils)?
  • What is cloudy/turbid appearance?
400

Certain pathogens can survive and replicate inside phagocytes after being engulfed, instead of being destroyed. Name one mechanism they use to do this.
Answer (any one):


  • What is preventing fusion of the phagosome with the lysosome?
  • What is resisting lysosomal enzymes?
  • What is escaping from the phagosome into the cytoplasm?
400

This protozoan parasite is transmitted by Anopheles mosquitoes and causes recurrent fever and hemolytic anemia.

Answer: What is Plasmodium

400

Give one example of a systemic autoimmune disease and one example of an organ‑specific autoimmune disease.

Answer (any one pair):

  • What are systemic lupus erythematosus (SLE) (systemic) and type 1 diabetes mellitus (organ‑specific)?
  • Or: What are rheumatoid arthritis (systemic) and Graves’ disease (organ‑specific)?
400

A patient with suspected sepsis arrives in the ED. Name two priority nursing actions in the first hour.
Answer (any two):


  • What is obtaining blood cultures before starting antibiotics?
  • What is starting broad‑spectrum IV antibiotics as ordered?
  • What is starting IV fluids (e.g., normal saline) to support blood pressure?
  • What is applying oxygen and monitoring vital signs closely?
400

Name one common bacterial cause and one common viral cause of meningitis in adults.
Answer (any one pair):

  • Bacterial: Neisseria meningitidis or Streptococcus pneumoniae
  • Viral: enteroviruses or herpes simplex virus (HSV)
  • Bacterial: Neisseria meningitidis or Streptococcus pneumoniae
  • Viral: enteroviruses or herpes simplex virus (HSV)
500

Some bacteria avoid phagocytosis by producing this external structure that impairs recognition and engulfment by immune cells.

Answer: What is a capsule?

500

Name one bacterial or viral pathogen and the specific type of tissue damage it commonly causes (e.g., toxin-mediated, direct cell lysis, etc.).
Answer (example):


  • What is **Clostridium
500

People with significant immune deficiency are usually advised to avoid this type of vaccine because it contains a weakened form of the micro‑organism that could still cause disease.

Answer: What are live attenuated vaccines?

500

Without treatment, bacteremia can progress to sepsis. Explain, in simple terms, what happens in the body when this progression occurs.

Answer: What is the immune system overreacts to the infection, causing widespread inflammation, leaky blood vessels, low blood pressure, and decreased blood flow to organs, which can lead to organ failure?

500

A patient with bacterial meningitis suddenly develops a purplish rash, very low blood pressure, and signs of shock. This dangerous complication is especially associated with meningococcal infection. Name it.

Answer: What is disseminated intravascular coagulation (DIC) or meningococcemia with septic shock?
(Allow either term depending on what you’ve emphasized in class.)