Gene Therapy
How many different methods of Bacterial Use in Gene Therapy are there?
4
Targets certain parts of the patient's body to replace faulty genes or add missing ones to affected cells, this method helps vectors to transport genes
Gene Transfer
3 common and powerful gene therapeutic tools for gene correction
1. ZFNs
2. CRISPR/Cas9
3. TALENs
Genes can be taken from one part of the body and taken to another to help it heal
Gene transfer
What is the goal of gene editing?
a. kill bad bacteria
b. replicate more of something
c. improve characteristics or correct a disorder
c. improve characteristics or correct a disorder
Are all bacteria used for helping in gene therapy?
No
An alteration of the genetic material of a living organism by inserting, replacing, or deleting a DNA sequence, the goal is to improve a characteristic of a crop or animal or to correct a genetic disorder
Gene editing
What was the bacteria example for gene correction?
Firmicutes
What was the example for gene transfer?
Salmonella
Can genetic material be added, removed, and/or altered?
ALL OF THE ABOVE
When is gene therapy needed?
To correct genes
Process of this inhibits or silences specific genes, usually helps prevent any sort of disease, also used to enhance characteristics or traits
Gene silencing
An imbalance in the gut microbial community that is associated with disease
Dysbiosis
This bacteria can be harmful if consumed in large amounts, however it can also be used to help fight cancer
Salmonella
What example of bacteria did we use for gene editing?
Streptococcus pyogenes (S. pyogenes)
Gives researchers a powerful tool for both repairing and mutating DNA, to discover gene functions and engineer new genetic variants
Gene correction
Did the Streptococcus pyogenes help to fix the genes that make people sick?
Yes