Hemoglobin
Hemoglobin that is most abundant in the normal newborn infant's red blood cells.
Hemoglobin F
A laboratory test that would be performed to evaluate the status of the body's iron stores.
Ferritin
Also known as crenated cells, they can be artifact on the PBS.
Echinocyte
Is the principle utilized by most hematology automation systesm to count and size RBCs
Electrical impedance
Can be used to eliminate smudge cells from the PBS.
Albumin
Will have an increased formation due to the failure of the RBC's hexose-monophosphate shunt to function properly.
Methemoglobin
This function of this analyte is to bind with iron and transfer it to the developing RBCs in the bone marrow.
Transferrin
Occurs when fibrin or leaions are present within the blood vessels
Schistocytes (or RBC fragments)
The test principle used to determine hemoglobin on the Sysmex instrument
Spectrophotometry
Can be performed to eliminate rouleuax from the PBS.
Plasma replacement procedure
Composed of four heme molecules and foud globin chains
This test is the recommended method of testing by the Clinical Laboratory Standards Institute (CLSI) for measuring hemoglobin in whole blood.
Cyanmethemoglobin
Abnormality cuased by a defect that renders the RBC membrane abnormally permeable to cations.
Stomatocytes
Makes it possible for RBCs and platelets to be analyzed in the same aperature bath by the hematology automation.
Electronic thresholds
These RBC inclusions are not visible on the Wright stained PBS
Heinz Bodies
Composed of 2 alpha and 2 beta chains, it constitutes about 96-98% of adult hemoglobin
Hemoglobin A
Identified by Prussian Blue Stain
Iron in the cells (siderocytes)
RBC abnormality that can be observed on the Wright Stained PBS and would be most indicative of an increased reticulocyte count.
Polychromasia
++++
Outside linearity (needs dilution)
Is used to determine whether teardrop morphology is artifact on the PBS
Teardrop tails (tails pointing in same direction)
An abnormal hemoglobin, its formation is irreversible.
Sulfhemoglobin
Specific test for spherocytosis (not RBC indice).
Osmotic fragility test
Increased membrane cholesterol to phospholipid ratio
Acanthocyte
Involves surrounding the cell stream within a stream of fluid, this creates pressure of the fluid which narrows the size of the cell stream until it is so narrow that only one cell is able to pass through.
Hydrodynamic focusing
Glass Slide Affect.