Pharmacokinetics I
The process by which a drug enters the blood stream from its site of administration.
What is absorption?
How a drug spreads throughout the body and reaches various tissues.
What is distribution?
-olol
What is a beta blocker?
TOP CARD
What are Ace Inhibitors?
&
What is teratogenic, orthostatic hypotension, potassium increase, cough, angioedema, renal impairment, dizziness.
We are used to treat severe pain, and we can be habit forming.
What are opioid analgesics?
OR
What are narcotic analgesics?
The final step in pharmacokinetics.
What is excretion/elimination?
Most drugs are excreted by the _______ in the form of _______.
What are the kidneys and what is urine?
-pril
What is an Ace Inhibitor?
FLUSHED
What are Nitrates?
&
What is flushing, lightheadedness, upset stomach (abdominal pain, n/v).
We are a class of drugs that can treat inflammation, by suppressing the immune response.
What are corticosteroids?
The biochemical modification of drugs.
What is metabolism?
The process where a drug is metabolized by the liver after being absorbed from the gastrointestinal tract, but before it enters systemic circulation.
What is first-pass metabolism/first pass effect?
-sartan
What is an Angiotensin II receptor blocker (ARB)?
DUAL
What are Fibric Acids?
&
What is dyspepsia, upper respiratory tract infections, abdominal pain, LFTs/CPK increased (dose related).
We are a class of drugs that treats insomnia.
What are hypnotics?
A critical factor in pharmacokinetics that influences the distribution, efficacy, and safety of drugs.
What is drug binding?
This route of administration can bypass the first-pass effect.
What is intravenous drug administration?
-mycin
What is a macrolide antibiotic?
CHOPDAT Lettuce
What is an ARB?
&
What is cough, headache, orthostatic hypotension, potassium increase, dizziness.
We are a class of drugs that treats depression.
What are SSRI's/antidepressants?
The process by which drug molecules undergo chemical modification within the body, which can affect their pharmacological activity and excretion.
What is biotransformation?
This is the result of first-pass metabolism/effect.
What is a reduced drug concentration (bioavailability)?
-asone or -ide
What are inhaled corticosteroids?
BAD FISH
What are Beta Blockers?
&
What is bradycardia, bronchospasms, AV block/arrhythmias, dizziness, fatigue, impotence, hypoglycemia (masked), hypotension.
We are a class of drugs that reduce LDLs.
What are statins?