Signs
Koplik spots on the buccal mucosa are a hallmark of this viral infection.
What is measles?
This bacterial pathogen was responsible for the 2011 German outbreak linked to contaminated fenugreek sprouts.
What is Shiga-toxin–producing E. coli?
This antibiotic class, discovered in the 1940s, revolutionized the treatment of Gram-positive infections.
What are penicillins (β-lactams)?
This newly emerging yeast, often resistant to multiple antifungals, is associated with hospital outbreaks worldwide.
What is Candida auris?
1st identified in ear canal of patient in Japan
This CCR5 antagonist is used as part of salvage therapy for multidrug-resistant HIV infections.
What is maraviroc?
The “ring-enhancing lesion” on brain imaging in an immunocompromised host is often caused by this protozoan.
What is Toxoplasma gondii?
This 1976 outbreak among American Legion convention attendees led to the identification of this bacterium.
What is Legionella pneumophila?
This live-attenuated vaccine for tuberculosis is still used in endemic regions.
What is BCG (Bacillus Calmette–Guérin)?
This saprophytic soil fungus is endemic to Southeast Asia and Northern Australia and is the cause of melioidosis.
What is Burkholderia pseudomallei?
This protozoan parasite, transmitted by sandflies, can cause diffuse cutaneous or visceral disease, including kala-azar.
What is Leishmania donovani?
The “bull’s-eye” erythema migrans rash is the hallmark of this tick-borne disease
What is Lyme disease?
The 2001 U.S. bioterrorism attacks involved spores of this bacterium.
What is Bacillus anthracis?
These organisms are potential reasons for false positive TB quants.
Mycobacterium
-marinum
-szulgai
-kansasii
The “chikungunya” virus gets its name from a word meaning “that which bends up” due to this clinical feature.
What is severe joint pain/arthralgia?
This enzyme is the target of bictegravir and dolutegravir.
What is HIV integrase?
The “saddleback” biphasic fever pattern is characteristic of this mosquito-borne virus.
What is dengue?
This severe viral outbreak in West Africa from 2013–2016 caused over 11,000 deaths.
What is Ebola virus disease?
This scientist demonstrated that H. pylori infection causes peptic ulcers by self-experimentation.
Who is Barry Marshall?
This protozoan parasite, transmitted by sandflies, can cause diffuse cutaneous or visceral disease, including kala-azar.
What is Leishmania donovani?
This bacterial disease struck American troops during the Spanish-American War at Camp Wikoff, linked to contaminated beef.
What is typhoid fever?
The triad of fever, rash, and eosinophilia after antibiotic exposure is a clue to this hypersensitivity syndrome.
What is DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms)?
This WHO-coordinated campaign eliminated this animal infection, making it the second disease eradicated after smallpox.
What is rinderpest virus?
The first recombinant DNA hepatitis B vaccine was licensed in this decade.
What is the 1980s?
"Blackwater fever,” characterized by dark urine and hemolysis, is a severe complication of infection with this parasite.
What is Plasmodium falciparum?
Pain in the right upper quadrant after drinking alcohol, known as Fitz-Hugh–Curtis syndrome, is caused by this pathogen.
What is Chlamydia trachomatis (or Neisseria gonorrhoeae)?