World Geography
Pop Culture & Entertainment
Science
Food and Drink
Wild Card
100

What country has the most time zones?

France

100

This actor voices both Donkey in Shrek and Mushu in Mulan.

Who is Eddie Murphy

100

The FDA's designation for treatments targeting serious conditions with preliminary evidence demonstrating substantial improvement over existing therapies.

What is Breakthrough Therapy Designation?

100

Which chemical compound is responsible for the spicy heat in chili peppers?

What is capsaicin?

100

In what year did the first iPhone release?

What is 2007?

200

This is the only U.S. state with a one-syllable name.

Maine

200

In what year did Taylor Swift release her album 1989?

What is 2014?

200

Which viral vector is most commonly used in gene therapy to deliver therapeutic genes to target cells?

What is an adeno-associated virus (AAV)?

200

What is the only U.S. state that produces coffee commercially?

What is Hawaii?

200

Which planet in our solar system has the shortest day?

What is Jupiter

300

Which African country is known as the “Rainbow Nation”?

South Africa

300

What is the highest-grossing movie of all time (not adjusted for inflation)?

What is Avatar?

300

In CAR-T cell therapy, T cells are engineered to express a receptor that recognizes a specific protein on cancer cells. What does CAR stand for?

What is chimeric antigen receptor?

300

Which country is the world’s largest producer of olive oil?

What is Spain?

300

Which ocean is the saltiest?

What is the Atlantic Ocean?

400

The Andes Mountains run through seven countries, but which one is home to the highest peak, Aconcagua?

What is Argentina?

400

What was the name of the first video game to feature Mario as a character?

What is Donkey Kong?

400

The FDA-approved gene therapy Zolgensma is used to treat what rare genetic disorder caused by mutations in the SMN1 gene?

What is spinal muscular atrophy (SMA)?

400

What is the name of the mother sauce made from milk thickened with a white roux?

What is béchamel?

400

What is the name of the ship used by Charles Darwin during his voyage that led to the theory of evolution?

What is HMS Beagle?

500

This mountain range separates Europe and Asia.

What are the Ural Mountains?

500

In Friends, what is Chandler Bing’s job?

What is a Statistical Analysis and Data Reconfiguration specialist?

500

This checkpoint protein, often targeted in immuno-oncology, prevents T cells from attacking cancer cells.

What is PD-1 (Programmed Death-1)?

500

What is the French term for a dish that is baked in a shallow dish and topped with a browned crust, often breadcrumbs or cheese?

What is gratin?

500

What is the only country in the world to have a flag that is not rectangular?

What is Nepal?