Designer Receptors Exclusively Activated by Designer Drugs (DREADDs)
4-aminobutyric acid
GABA
In Greek, "Seahorse"
Hippocampus
Phineas Gage didn't need it
Frontal Lobe
Noninvasive brain stimulation using magnetic fields.
Transcranial Magnetic Stimulation
The ligand of choice for DREADDs
Clozapine N-oxide
4-(2-Aminoethyl)benzene-1,2-diol
Dopamine
In Latin, "Pine Cone"
Pineal Gland
Midbrain nucleus not just for eye movements
Edinger-Westphal nucleus
Functional imaging technique using radiotracers
Positron Emission Tomography
Canonical excitatory DREADD
HM3Dq
(2-Acetoxyethyl) trimethylammonium
Acetylcholine
Via Latin from Greek "Almond"
Amygdala
I release Prolactin
What does TRAP stand for?
translating-ribosome affinity purification
Canonical inhibitory DREADD
hM4Di
2-(1H-Imidazol-4-yl)ethanamine
Histamine
In Latin "Upper Hill"
Superior Colliculus
I recognize faces.
Fusiform Face Area
One of two methods used to originally measure biogenic amines using electrodes.
Fast-Scan Cyclic Voltammetry or Amperometry
The C in CNO belongs to this class of drugs.
Clozapine - atypical antipsychotics
(2S)-2-aminopentanedioic acid
Glutamate
In Latin, "Tuft of Wool"
The Flocculus
I connect the temporal and inferior parietal cortex to the frontal lobe.
arcuate fasciculus
Trepanation