Building Blocks
Amino Acid Construction
Macromolecule Mix-Up
Essential Processes
From Atoms to Life
100

What are the three main elements found in sugar molecules?

Carbon, hydrogen, and oxygen

100

Which element must be added to carbon, hydrogen, and oxygen to form amino acids?

Nitrogen

100

What macromolecule is made from long chains of amino acids?

Proteins

100

Which process breaks down sugar molecules to release energy?

Cellular respiration

100

What type of bond holds atoms together in molecules?

Covalent bond

200

What type of molecule is glucose?

A carbohydrate (monosaccharide)

200

What type of bond links amino acids together in proteins?

Peptide bond

200

Which macromolecule stores genetic information?

Nucleic acids (DNA/RNA)

200

What is the name of the process that builds proteins from amino acids?

Protein synthesis (translation)

200

What is the main role of oxygen in cellular processes?

It is the final electron acceptor in cellular respiration, enabling ATP production.

300

How does the structure of glucose make it a good energy source?

Its bonds store chemical energy that can be easily broken to release ATP.

300

Why does the addition of nitrogen change the function of a molecule compared to glucose?

Nitrogen enables amino groups, allowing molecules to form proteins with structural and functional roles.

300

Compare carbohydrates and proteins in terms of structure and function.

Carbohydrates provide energy/storage (C, H, O); proteins perform structural, enzymatic, and signaling functions (C, H, O, N, S).

300

Explain how the energy from glucose breakdown is connected to building amino acids.

ATP from glucose provides the energy needed to synthesize amino acids and proteins.

300

How does rearranging the same elements create molecules with different functions?

Different bonding patterns and structures lead to unique properties and roles.

400

Compare the elements in glucose with the elements in an amino acid.

Glucose has C, H, O; amino acids also have N (and sometimes S).

400

Predict what might happen if cells could not access nitrogen for building amino acids.

Proteins couldn’t be built → cells couldn’t grow, repair, or function.

400

How do elements like sulfur or phosphorus expand the diversity of macromolecules?

They allow unique chemical properties, such as disulfide bonds in proteins or phosphate groups in DNA.

400

How does protein function in the body differ from the role of carbohydrates?

Carbohydrates store/provide energy; proteins build structures, act as enzymes, and regulate processes.

400

Why is it important that carbon can form four bonds?

It allows carbon to build diverse, stable, complex molecules (chains, rings, branching).

500

Explain how a cell could use carbon from glucose to build a protein.

Cells break down glucose for carbon skeletons, add nitrogen and other elements, then link amino acids together into proteins.

500

Construct an explanation for how glucose can serve as a starting point for amino acid synthesis in cells.

Glucose provides carbon skeletons through metabolic pathways; cells add nitrogen to form amino acids, which are assembled into proteins.

500

Argue why life could not exist with only carbon, hydrogen, and oxygen.

Without nitrogen, phosphorus, and sulfur, essential macromolecules (proteins, nucleic acids, phospholipids) could not form.

500

Revise an explanation for how the cycling of carbon through sugars and proteins supports life at the ecosystem level.

Plants fix carbon into sugars; animals eat sugars and build proteins; decomposers recycle carbon back into the environment, sustaining the cycle of life.

500

Construct an explanation for how small molecular changes can lead to large differences in biological function (example: hemoglobin vs. sickle-cell hemoglobin).

A single amino acid substitution changes protein shape, affecting oxygen transport and causing disease, showing how small changes can greatly impact life.