Lore
References
Mechanics
Item Effect
History kinda idk its misc category
100

This transformation is a reincarnation of Isaac's late cat

Who is Guppy

100

This item is in reference to Edmunds most popular game before Binding of Isaac, Super Meat Boy, allowing you to have the protagonist as your familiar

What is Cube of Meat

100

This mechanic randomly makes enemies harder to kill and/or giving them additional power for the chance of an extra reward

What are Champion Enemies

100

This item gives you a red beam which you must charge, this replaces your normal tears

What is Brimstone?

100

This character is the antagonist of the Super Meat Boy Franchise

Who is Dr. Fetus

200

This character is revealed to be the narrator of the game

Who is Isaacs Dad

200

This usable item references an old card in Magic: The Gatherings history, allowing you to draw 3 cards

What is Ancient Recall

200

This mechanic roughly determines the rarity of an item, often correlating to how powerful the item is

What is Item Quality

200

This item takes you to a special floor which allows you to pick up any item from the game you want, but you only get one

What is Death Certificate

200

This character is the protagonist of a deck building roguelike game that doubles as a prequal to one of Edmunds games

Who is Bumbo

300

This character is the "voice of god" that speaks to Isaac's Mom

Who is The Lost

300

This activated item references the creator of Minecraft in the name and references the game in its ability

What is Notched Axe

300

This mechanic gives players unique ways to play and enjoy the game while still getting unlocks upon completion

What are Challenges

300

This item gives +2 Health

What is Raw Liver

300

This was the name for Binding of Isaac's first expansion

What is Wrath of The Lamb

400

This boss is an analogy for Isaac's uncle

Who is Sloth

400

This activated item references a popular series of books that cover the basics of various subjects

What is Telepathy for Dummies

400

This variant of a usable item allows you to use the item over and over with an increasing chance of it dissapearing

What is a Golden Pill

400

This trinket increases the chance of finding a Tarot card after clearing a room or from chests

What is Ace of Spades

400

This mod's developers were hired to work on Repentance, carrying over a lot of the mods content

What is Anti-Birth

500

This is the name of Isaac's Mom

Who is Magdalene O. Moriah

500

This character is in reference to a character who was the face of a lot of Edmunds most early games published to Newgrounds

Who is Blue Baby or ???

500

This mechanic lowers the amount of hearts you can have total, only being able to remove at a Confessional 

What are Broken Hearts

500

This item gives you +2 luck and makes you not take damage from poison, toxic, gas, and burn effects. It also makes you immune to fear and confusion

What is Evil Charm

500

This BOI boss has gotten Edmund into hot water for its appearance, although it is simply a callback to one of his old flash games.

Who is Steven