- penicillin
- isoniazid
- vancomycin
- erythromycin
- cephalosporin
erythromycin
identify the features of Koch's postulates
1. identify infectious agent
2. isolate infectious agent
3. inoculate a nonhuman subject and observe
4. re-isolate the infectious agent
the greatest number of pathogens enter the body from where
respiratory system
artificial vs natural immunity
artifical = vaccines
natural = your parents, etc
describe the differences between maculopaplar and vesicular rashes
pus vs no pus
why is penicillin less toxic than other antibiotics
cell wall
characteristics of endotoxins vs exotoxins
chemical that hydrolyzes the peptidoglycan in bacteria
lysozyme
describe Edward Jenner's role in the inoculation process
virulence factor of MRSA
coagulase
what does trimethoprim inhibit
folic and nucleic acid
lactoferrin, lactobacillus, oligosaccharide, mom bacteria
why are inflammation, fever, phagocytosis, and antimicrobial products considered innate?
Not antigen specific, happen regardless of specific immunity
whole cell vaccines vs subunit vaccines
whole cell uses the whole cell, subunit uses parts
causative agent of smallpox
variola virus
penicillium
bacillus
staphylococcus
streptomycin
cephalosporium
Name 3 most common nosocomial infections
c diff
staph aureus
e coli
characteristics of inflammation
what are memory cells
function of specific immunity that provides long lasting protection against certain antigens
describe some differences between bacterial and viral conjunctivitis
bacterial - milky discharge
viral - clear discharge
name the four mechanisms of drug resistance
1. new enzyme
2. alternative metabolic pathway
3. MDR pumps
4. binding sites decrease
5. uptake/absorption decreases
5 steps of establishing disease in a host
1. portal of entry
2. adhesion
3. surviving host defenses
4. causing illness
5. portal of exit
PAMPs vs PRR
PAMP on bacteria, PRR on us
describe the differences between B and T cells
bone marrow v thymus
B cells low numbers in blood, T cells high numbers
B cells - cortex of lymphatic organs
T cells - paracortial regions of lymphatic organs
B cells use immonuglobulin as surface receptors, T cells use T cell surface receptors
description of the most contagious disease known to man
measles