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100
what are the fat soluble vitamins?
ADEK
100
where is vitamin A found
Liver and leafy vegetables
100
what is TTP's function
cofactor for several dehydrogenase rxns
100
How many ATP are produced from Riboflavin?
2 ATP….riboflavin = B2 = 2 ATP
100
What is B3 derived from?
Tryptophan ?
200
What are 2 malabsorption syndromes with steatorrhea that can cause fat-soluble vitamin deficiencies?
CF Celiacs
200
what version of vitamin A (retinol) is used to treat wrinkles and acne
Retin - A
200
what dehydrogenase rxns is TTP required for…list ALL 4
pyruvate dehydrogenase? alpha ketoglutarate dehydrogenase ?transketolase (HMP shunt) branched chain ketoacid dehydrogenase
200
Components of riboflavin are used as cofactors in what reaction in the TCA cycle?
succinate dehydrogenase rxn in TCA cycle
200
synthesis of B3 requires what other vitamins?
B2 and B6?
300
What does TPP abbreviate for ?
Thiamine pyrophosphate
300
deficiency in vitamin A will cause what symptoms (list any 3)?
night blindness (nyctalopia)? dry, scaly, skin (xerosis cutis)? corneal degeneration (keratomalacia)? bitot spots on conjunctiva ?immunosuppression
300
pyruvate dehydrogenase?alpha ketoglutarate dehydrogenase?transketolase (HMP shunt)?branched chain ketoacid dehydrogenase
More ATP depletion,,,,will worsen condition
300
What are the symptoms seen in riboflavin deficiency?
cheilosis ?corneal vascularization
300
What is niacin used to treat commonly?
Dyslipidemia – will lover VLDL and raise HDL
400
what is another name for B5?
Pantothenic acid
400
Vit A is essential for differentiation of …..
normal differentiation of epithelial cells into specialized tissue
400
What is a Wernicke-korsakoff syndrome triad?
Confusion, ophthalmoplegia and ataxia
400
What are 2 main functions of pantothenic acid?
-essential component of CoA (a cofactor for acyl transfers) -fatty acid synthase
400
What are the infamous D’s of Vit 3 deficiency?
diarrhea ?dementia (hallucinations) ?dermatitis
500
what are all the water soluble vitamins?
B1, B2, B3, B4, B5, B6, B6, B9, B12, Vit C
500
3 signs/symptoms of CHRONIC Vit A Toxicity
alopecia? dry skin (scaliness)? hepatic toxicity and enlargement?arthralgias? pseudotumor cerebri
500
what anatomical structures are damaged in Wernicke-Korsakoff
medial dorsal nucleus of thalamus ?mammillary bodies
500
what are the symptoms of B5 deficiency, list 3.
dermatitis? enteritis? alopecia? adrenal insufficiency
500
How does hartnup disease cause pellagra?
decreases tryptophan absorption