Attenuated, Killed, Toxoid, Subunit or Conjugate
Unable to invade healthy surrounding tissue, incapable of indefinite growth
What is benign?
Mutated TAP genes
Stage where CD4 cells are below 200
What is AIDS?
Begins 7-10 days post transplantation
What is Acute rejection?
Spread to other tissues
What is metastasize?
Deficiency in CD40L
Important in the survival of selected B and T cells during maturation
What is bcl2?
Transplant between genetically different members
What is allograft?
Carcinoembryonic antigen (CEA) and Alpha-fetoprotein (AFP)
What are oncofetal antigens?
Extremely low levels of IgG, absence of other isotypes
Mumps, Hepatitis B or Polio (Salk): one which mounts the most vigorous response
What is mumps?
Baboon heart into a human
What is xenograft?
Caused by defects in genes involved in normal DNA repair
What is Xeroderma pigmentosum (XP)?
Deletion of regions on chromosome 22, including TBX1
B cells are locked in the pro– to pre–B-cell stage
What is agammaglobulinemia?
Reaction due to donor T cells that attack recipient tissue
What is GVHD?
Encodes a nuclear phosphoprotein with multiple roles, including involvement in growth arrest, apoptosis, and DNA repair
Mutations in the lysosomal trafficking regulator (LYST) gene
Mutated and inactive FoxP3 gene
What is IPEX?
Recipient: A3/A8, B1/B8, C4/C1
What donor is best:
1: A3/A4, B2/B7, C4/C32: A3/A8, B4/B9, C2/C6
3: A8/A6, B1/B4, C6/C2
4: A2/A6, B8/B4, C1/C1
What is donor 4?