Stem Cells
What are totipotent stem cells?
The mode of inheritance of sickle cell anemia
What is autosomal recessive?
What the acronym CRISPR stands for
What is Clustered Regularly Interspaced Short Palindromic Repeats?
The first stage of cancer development characterized by enhanced cell division
What is hyperplasia?
This category of cancer genes usually act dominantly and incur gain of function mutations
What are oncogenes?
The 4 genes referred to as Yamanaka factors
What is Oct3/4, Sox2, Klf4, and c-Myc?
What is four?
The 2 components necessary for CRISPR gene editing to work
What is Cas9 and guide RNA?
Type of cancer derived from bone
What is sarcoma?
A mechanism of stem cell reprogramming involving an oocyte and a somatic cell
What is nuclear transfer?
The parasite that can not readily infect individuals that are heterozygous for the sickle cell mutation
What is plasmodium?
This gene editing technology binds a nucleotide triplet
What is zinc finger nuclease?
creates pyrimidine dimers in DNA
What is UV-B?
Mutations in this gene are the most common observed in cancer
What is TP53?
If one stem cell happens to divide into two daughter cells, another stem cell will instead produce two mother cells
What is stochastic differentiation?
Hydroxyurea increases production of this fetal protein
What is gamma hemoglobin?
The nuclease that functions in the TALEN gene editing technique
What is Fok1?
The enzyme that forms acetate during alcohol breakdown
What is ALDH?
The BRCA genes exhibit this function
What is caretaker/genome stability?
What is an embryoid body?
The major symptom that causes extreme pain in sickle cell patients
What is a vaso-occlusive crisis?
This type of double stranded break repair requires a donor template to be present
What is homology directed repair?
A common way for inherited cancer predisposition to turn cancerous, can be due to deletions, nondisjunction, methylation, etc.
What is loss of heterozygosity
This cell surface receptor gene is often seen amplified in breast cancer
What is ERBB2/HER2?