Chapter 12/13
Chapter 14
Chapter 15/16
Chapter 17
BME
100

Dideoxynucleotides are used in:

both Sanger and high-throughput sequencing at all times.

neither Sanger nor high-throughput sequencing.

high-throughput DNA sequencing but not in Sanger sequencing.

both Sanger and high-throughput sequencing, but not at all times.

Sanger sequencing but not in high-throughput DNA sequencing.



Sanger sequencing but not in high-throughput DNA sequencing

100

What is formed when any two branches diverge in a phylogenetic tree?

A root
A module
A node
A lineage
A population


A node

100

The vegetable we know as the potato resulted from naturally occurring genome doubling within one species. In other words, the potato has twice as many chromosomes as the ancestor it was derived from. The potato could therefore be described as being the result of the process known as


allopolyploidy.
allopatric speciation.
autopolyploidy.
hybridization.
hybrid sterility.


autopolyploidy

100

Darwin’s finches on the Galápagos Islands have diverged primarily via _______ speciation, and they exhibit diverse morphologies owing to differences in _______. 

allopatric; their diets 
sympatric; predation pressures 
allopatric; drought tolerance adaptations 
sympatric; their diets 
allopatric; predation pressures 


allopatric; their diets

100

What are the six departments of engineering at the University of Iowa.

Biomedical Engineering

Chemical and Biochemical Engineering

Industrial and Systems Engineering

Civil and Environmental Engineering

Mechanical Engineering

Electrical and Computer Engineering

200

Which is a major difference between LINEs and SINEs?

LINEs make RNA copies of themselves, whereas SINEs do not.

SINEs make RNA copies of themselves, whereas LINEs do not.

SINEs are larger than LINEs.

Proteins sometimes are translated from LINEs but they never are from SINEs.

SINEs can move from place to place in the genome, whereas LINEs cannot.

Proteins sometimes are translated from LINEs but they never are from SINEs.

200

 A molecular clock assumes that the genes used in an analysis 

do not alter their rates in different lineages. 
are evolving rapidly. 
are evolving slowly. 
alter their rates in different lineages. 
are all evolving at the same rate. 


do not alter their rates in different lineages. 
200

 Which statement about synonymous mutations is true? 

They are likely to be neutral because they do not change the phenotype. 
They are likely to be neutral because they affect the structure of the protein. 
They are unlikely to be neutral because they change the activity of the protein. 
They are unlikely to be neutral because they will likely be lethal. 
They are likely to be neutral because they change the amino acid composition of the protein. 


They are likely to be neutral because they do not change the phenotype. 
200

Which statement about oxygen and ancient Earth is true? 

The first Oxygen in the atmosphere came from the photosynthesis of land plants 
 The oxygen-generating cyanobacteria have gone extinct. 
 Oxygen concentration increased from near zero to near present-day levels in a nearly straight line upwards. 
 The atmosphere of early Earth contained almost as much free oxygen as present-day Earth, but most of this oxygen was lost in the Cambrian.  
Early bacteria generated free oxygen as a by-product of the chemical splitting of water.


Early bacteria generated free oxygen as a by-product of the chemical splitting of water.

200

How many elevators are in the Seamans Center?

7

300

In functional genomics, biologists use sequence information to identify the functions of various regions of genomes. Which kinds of information could not be obtained from a genome sequence? 

Noncoding repetitive repeats 
Genes encoding for transcription factors 
rRNA genes 
Amino acid sequences of proteins 
Metabolite levels in cells 


Metabolite levels in cells 
300

Repetitive DNA sequences usually evolve very quickly. Based on this fact, molecules that have a rapid mutation rate are used to study relationships among

phyla of animals.
very closely related species.
organisms that diverged long ago.
extinct organisms.
all organisms.


very closely related species

300

In a sequence of DNA taken from various species of snails, researchers have found that the rates of nonsynonymous substitutions and synonymous substitutions are roughly the same. What can we infer from this pattern?

Strong positive selection is acting on this gene.
This gene has a high mutation rate.
This gene has a low mutation rate.
Strong stabilizing selection is acting on this gene.
Most of the amino acid substitutions at this gene are neutral.


Most of the amino acid substitutions at this gene are neutral.
300

As compared to anaerobic metabolism, aerobic metabolism is advantageous to cells because it 

 permits the growth of smaller, more complex cells. 
  proceeds at a less rapid rate.  
 allowed aerobic organisms to replace all anaerobes on Earth.  
 allowed photosynthetic organisms to develop.  
 harvests energy more efficiently. 


harvests energy more efficiently

300

What room number is the Kitchenette, the room with the only public microwave in the Seaman Center?

3362

2329

1418

5012

2329

400

Various populations of a beetle species are examined over several generations. Initially, the populations are genetically distinct, but over time they become similar at a number of loci throughout the genome. What is the most likely reason for this decrease in genetic differentiation?

Genetic drift
Natural selection
A founder effect
Mutation
Gene flow


Gene flow

400

Consider five species of toads. Species A and B are sister species. Species C and D are also sister species. The clade containing species A and B is sister to the clade containing species C and D. Species E is sister to the clade containing A, B, C, and D. Not counting the root as a node, how many nodes would be found in a phylogenetic tree containing just species A, B, C, and D?

2

400

A gene family has been accumulating nucleotide substitutions at a rate of 0.25 substitutions per million years. On average, there have been 80 substitutions between the common ancestor of this gene family and each of the various living forms of this gene. How many substitutions are likely to have evolved between any pair of living forms of genes from this gene family?

160
320
40
20
80


160

400

The heat that drives plate tectonics comes from  


 chemical energy from bacteria 

 radiant energy from the sun. 

 radioactive decay inside Earth’s core. 

 kinetic energy from meteorite collisions. 


  radioactive decay inside Earth’s core. 
400

List the four "pre-approved" BME focus areas.

  • Bioimaging
  • Biomechanics and Biomaterials
  • Cellular Engineering
  • Computational Bioengineering
500

_______ selection operates if individuals within a population with the smallest and largest body sizes have fewer offspring than those of average body size. 

Disruptive 
Destabilizing 
Stabilizing 
Directional 
Sexual 


Stabilizing

500

Which event is least likely to occur after a gene duplication event?

One gene retains its function, while the other becomes a pseudogene.
Both genes become pseudogenes.
Both genes retain their function, but they are expressed in different tissues.
One gene retains its function, while the other evolves to have a new function.
Both genes retain their function, but they are expressed at different times.


Both genes become pseudogenes

500

Which statement about speciation is true?

A single lineage always splits to form species after a few generations.
Evolutionary changes to an organism always result in a species.
Speciation relies on gene flow.
Genetic changes preventing reproduction between formerly interbreeding populations can lead to speciation.
Only the biological species concept is concerned with reproductive isolation.


Genetic changes preventing reproduction between formerly interbreeding populations can lead to speciation.
500

 What led to the mass extinction at the end of the Cretaceous period? 

The breakup of a supercontinent 
An increase in the concentration of Earth’s oxygen 
A meteorite striking Earth 
Human activity 
All of Earth’s continents coming together to form a supercontinent 


A meteorite striking Earth

500

List the four focus areas for Mechanical Engineering.

  • Design
  • Energy & Environment
  • Manufacturing
  • Robotics and Autonomous Systems