History
The 18th Amendment/Volstead Act
What is prohibition?
Absorption
What is the amount of time it takes the drug to leave the site of administration and enter the blood stream?
The parasympathetic nervous system vs the sympathetic nervous system
What is the "rest and digest" (parasympathetic) vs "fight of flight" response (sympathetic)?
The major neurotransmitter in addiction
What is dopamine?
The basic difference between the medical and moral model
What is the perspective on choice (moral model) and no choice (medical model)?
The 21st Amendment
What is the amendment that repealed prohibition?
Bioavailability
What is the amount of the drug that gets to the target organ?
Agonist vs. Antagonist
What is a drug that binds to the neurotransmitter’s receptor and mimics or facilitates the effects of a neurotransmitter (agonist) vs a drug that binds to the neurotransmitter’s receptor and blocks the effects of the neurotransmitter (antagonist)?
The part of the brain that stores emotion laden memories
What is the amygdala?
Multiply the half-life by five to get the...
What is the steady state and the time it takes the drug to clear?
The Harrison Act of 1914
What is the Act that stated only physicians could be licensed to prescribe opioids and cocaine for treatment of disease (other than addiction)?
Metabolism is typically done by the ____ and and excretion by the ____
What is the liver (metabolism) and the kidneys (excretion)?
Neurotransmission is ____ in a neuron and ____ in the synapse
What is electrical in a neuron and chemical in the synapse?
Positive reinforcement vs. negative reinforcement
What is an enhancing effect that makes someone want to use the drug again (euphoria) vs a subtracting effect that makes someone want to use the drug again (subtraction of withdrawal)?
The difference between pharmacokinetics and pharmacodynamics
What is what the body does to the drug (pharmacokinetics) vs what the drug does to the body (pharmacodynamics)?
DEA vs FDA
What is enforces laws and regulations vs concerned about safety of medications?
Three factors that can affect drug metabolism
What is age, gender, genetics, race, organ disease, environment, drug interactions, emotional state?
The four parts of a neuron
What is the cell body, axon, axon terminal, and dendrites?
The key elements of the reward pathway
What is the VTA, Nucleus Accumbens, Prefrontal Cortex, and Amygdala?
One drug in each of the following categories: Schedule I, Schedule II, Schedule III
What is heroin, weed, LSD (I), fentanyl, hydrocodone, oxycodone, Ritalin (II), and buprenorphine, and Tylenol with codeine (III)?
Three of the five historical themes
What is 1. Humans have a basic need to cope with their environment and enhance existence. 2. Brain chemistry is affected by psychoactive drugs, behavioral addictions, and mental illness to induce an altered state of consciousness. 3. The ruling classes, governments, and businesses as well as criminal organizations have been involved in growing, manufacturing, distributing, taxing, and prohibiting drugs. 4. Technological advances in refining, synthesizing, and manufacturing drugs have increased the potency of substances. 5. The development of faster and more efficient methods of putting drugs into the body has intensified effects?
The routes of administration from slowest to fastest
What is transdermal (skin patch), oral, SC, MC, mucous membrane absorption, IV, and inhalation?
CNS vs PNS
What is the brain, brainstem, and spinal cord (CNS) vs "everything else": the autonomic and somatic nervous system, and the sympathetic and parasympathetic nervous system (PNS)?
Three brain lobes and their basic function
What is frontal lobe (executive functioning, planning, parts of speech, problem solving, emotions), parietal lobe (movement, spatial orientation, recognition, perception of stimuli), occipital lobe (visual processing), cerebellum (regulation and coordination of movement, posture, balance, motivation, concentration), and temporal lobe (perception and recognition of auditory stimuli, memory, speech)?
The three stages of addiction
What is 1. binge/intoxication 2. withdrawal/negative affect 3. preoccupation/anticipation?