Informatics? What are those? (Concepts)
The Lego Movie (Building Blocks)
The Horse's Mouth (Resources)
Anything You Can Do I Can Do Better (Skills)
He's Got Issues (Issues)
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This term is often used erroneously to refer to the broad field of biomedical informatics.
What is bioinformatics? Originally referring to the informatics of biotechnology (DNA and protein sequencing), it is typically used for informatics related to molecular biology and computational biology, but it does not cover the domain of clinical informatics.
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This system contains comprehensive patient information, including health maintenance data.
What is an Electronic Health Record (EHR)? EHRs typically support additional functions such as computerized provider order entry and clinical decision support.
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This resource at NLM includes 3.6 million full-text articles.
What is PubMed Central? PMC is a repository for journal literature deposited by participating publishers, as well as for author manuscripts that have been submitted in compliance with the Public Access Policy mandated by NIH and similar policies of other research funding agencies.
100
Developed at the Massachusetts General Hospital, this computer language is the basis for many electronic health record system.
What is MUMPS? This acronym for the second ANSI-standard computer language stands for Massachusetts (General Hospital) Utility Multi-Programming System .
100
Six of the seven billion people in the world have access to these.
What are cell phones? But 1.5 billion of them don't use them on the toilet (due to lack of access).
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This popular open source system is being used around the world for electronic capture of research data.
What is REDCap? REDCap currently has 1,609 active institutional partners in 90 countries.
200
This messaging standard has been widely adopted for the exchange of laboratory and other EHR data.
What is HL7? Version 2 has been popular but has many limitations. Version 3 adoption has proved cumbersome. A new light-weight version called FHIR (pronounced "fire") has been developed to address these issues.
200
This NLM resource has clinical study results, including those that have not yet appeared in the published in literature.
What is ClinicalTrials.gov? The Food and Drug Administration Amendments Act of 2007 (FDAAA; pronounced "fa-DAA") and the International Council of Medical Journal Editors both require researchers to register their trials prior to subject enrollment.
200
This emerging approach for disease prevention and treatment takes into account people's individual variations in genes, environment and lifestyle.
What is precision medicine? Launched with a $215 million investment in the President’s 2016 Budget, the Precision Medicine Initiative will pioneer a new model of patient-powered research that promises to accelerate biomedical discoveries and provide clinicians with new tools, knowledge, and therapies to select which treatments will work best for which patients.
200
This is considered the most important desideratum of controlled biomedical terminologies.
What is Concept Orientation? Establishing the idea that the unit of discourse is the concept, not the term or name for the concept, it includes the requirements for nonvagueness, nonredundancy and nonredundnacy, and it is the basis for other desiderata, such as concept permanence.
300
If LOINC is the question, this is the answer.
What is SNOMED? The LOINC committee and the International Health Terminology Standards Development Organization (IHTSDO) are coordinating the terminologies for these two domains.
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These context-aware web links attempt to anticipate and resolve computer users' information needs.
What are infobuttons? HL7-compliant infobutton managers require only insitution, task and concept of interest to select resources and HL7-compliant resources require only the concept of interest to retrieve relevant knowledge.
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This NLM resource assists emergency responders in hazardous material incidents.
What is WISER? WISER provides a wide range of information on hazardous substances, including substance identification support, physical characteristics, human health information, and containment and suppression advice.
300
Unlike most genetic material, this substance is passed to offspring from the mother only.
What is mitochondrial DNA? Mitochondria do not contain anywhere near the amount of DNA needed to code for all mitochondria-specific proteins, however, a billion or so years of evolution could account for a progressive loss of independence.
300
This is responsible for physicians and nurses overriding up to 96% of alerts from clinical decision support systems.
What is alert fatigue? Alert logic typically does not have access to information that allows clinicians to override alerts safely (such as past medical history) and after a series of false positives, fatigue sets in.
400
This person who applies formal methods to organize knowledge of human health and disease, and making it useful for problem solving.
What is a biomedical informatician? Many people meet the definition of "biomedical informatician" and don't realize it.
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This standard is used to transmit information that enables hardware from multiple manufacturers to communicate and share images.
What is DICOM? A DICOM data object consists of a number of attributes, including items such as name, ID, etc., and also one special attribute containing the image pixel data.
400
This ad-hoc query system provides a Wonderland of publicly available public health data.
What is CDC Wonder? CDC Wonder provides direct access to over 18 databases on birth, death, populations and environment, as well as guidelines and access to other query systems such as Healthy People 2010 and the Mortality and Morbidity Weekly.
400
.More complex than simple NLP, symbolic NLP makes use of this language knowledge resource.
What is a grammar? Grammar-based NLP makes use of structural rules of a language, as opposed simple statistical occurrence patterns found in text corpora.
400
This law includes a provision to protect personal health information.
What is the Health Insurance Portability and Accountability Act (HIPAA)? Data can be considered de-identified by removal of 18 "safe harbor" items (one of which is "anything else") or by a method certified by a privacy expert.
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This interdisciplinary field of processes and systems to extract knowledge or insights from large volumes of data in various forms, either structured or unstructured, is a continuation of data analysis fields such as data mining and predictive analytics, and knowledge discovery in databases.
What is data science? Data science is a new priority of the National Institutes of Health, which has brought in an Associate Director for Data Science and inititated a number of BD2k, or "big data to knowledge" research and training programs.
500
These high-quality standard terminologies are being required for exchange of laboratory and medication data, respectively.
What are LOINC and RXNorm? Both of these can be obtained from the UMLS.
500
This is the "B" word in the full name of NCBI.
What is "biotechnology"? Although the general definition of this term is "any technological application that uses biological systems, living organisms or derivatives thereof, to make or modify products or processes for specific use" it often is used to refer to the technology of large molecule sequencing.
500
This adjustment is necessary to determine if a comparison is "statistically significant" when many comparisons are possible.
What is the Bonferonni Correction? This correction is calculated by dividing the threshhold for statistical significance (usually 5%) by the number of hypotheses being tested simultaneously to produce a new threshhold.
500
Although its name was politically correct when it was established in 1990, the name of this Bethesda, Maryland organization, the professional home for biomedical informatics, is a bit anachronistic.
What is the American Medical Informatics Association (AMIA)? AMIA's Annual Symposium is the largest annual biomedical informatics conference in the world, usually held in November, usually in Washington, DC.