Lab Techniques
Personal Genetics
CRISPR
GDRP
Thanksgiving Facts
100

What technique separates molecules by size and charge?

Gel electrophoresis

100

This technology screens embryos in vitro for their genetic makeup.

Preimplantation Genetic Diagnosis (PGD)

100

What is the purpose of CRISPR technology?

Gene editing

100

This disease involves a build up of mucus in the lungs, among other places, due to a mutation in the CFTR gene.

Cystic Fibrosis

100

We should all give thanks to this U.S. president who proclaimed a national day of Thanksgiving in 1789

Washington

200

What technique makes copies of DNA?

PCR

200

This chemical has a bitter taste--only if you have the dominant allele for the taste receptors!

PTC

200

Which enzyme acts as the "molecular scissors" in a CRISPR system?

Cas9

200

A third copy of the 21st chromosomes causes this syndrome.

Down Syndrome

200

While the turkey is cooking, we can watch this NFL team that played more Turkey Day games than any other

Detroit Lions

300

What technique cuts DNA at a specific sequence?

Restriction enzyme digest

300

What website allows any scientist to compare a genetic sequence to a massive genomic database?

BLAST

300

What is the name of the molecule that allows CRISPR technology to recognize the target DNA sequence?

gRNA (guide RNA)

300
A CRISPR therapy called exa-cel is in the process of FDA approval to treat this disease of the red blood cells.

Sickle Cell Disease (or Anemia)

300

I'm decorating with a cornucopia inspired by the magical horn of Amalthea, who nursed this Greek god when he was a baby

Zeus

400

This is the enzyme that copies the target DNA in PCR.

taq DNA Polymerase

400

Some people choose to get a genetic test for this gene, whose presence increases the risk of developing breast or ovarian cancer.

BRCA (1 or 2)

400

What gene was edited in Lulu and Nana, the "CRISPR twins" born in 2018?

CCR5

400

This X-linked disorder that affects the protein dystrophin has recently had a new exon-skipping gene therapy treatment approved by the FDA!

Duchenne Muscular Dystrophy

400

If we eat enough of these cranberries we won't get scurvy because they're chock full of this vitamin

C

500

The wells of gel in electrophoresis need to face towards this electrode when a DNA sample is run.

Negative

500

This type of experimental reproductive technology is currently banned in the United States, but when used in the UK produces is often called a "3 parent embryo"

Mitochondrial Replacement Therapy

500
What does CRISPR stand for?

Clustered Regularly Interspaced Short Palindromic  Repeats

500

This neurodegenerative disorder is due to a CAG repeat in a protein expressed in the brain.

Huntington's Disease

500

The sedative effects of turkey have been attributed to this amino acid, sold as a sleep aid until 1990

Tryptophan