Modern Pharmaceutical Biotechnology
Define recombinant DNA technology
Taking the genetic material from 2 organisms and recombining them to create new genetic material
Why is cystic fibrosis a good candidate for treatment using gene therapy?
Cystic fibrosis involves only 1 mutated gene and there currently is no cure
What types of cancer do we currently treat with a vaccine
Prostate Cancer
What are some examples of autoimmune diseases
What I currently considered the least reliable disease
Flu
Where do we get the genetic information to create modern synthetic insulin
Humans
What is necessary for a condition to be eligible for treatment with gene therapy?
Disease has to be incurable and involve the mutation of only 1 gene
What do preventative cancer vaccines protect against
HPV- Cervical Cancer
Hepatitis B- Liver Cancer
What is an autoimmune disease
A disease where the immune system attacks the body
What does the pneumococcal vaccine protect against
Pneumonia
What organisms were the first forms of insulin derived from?
Cow and Pig
What is the gene that causes cystic fibrosis
CFTR gene
If a virus is oncolytic it may require additional treatment with what?
Why are biologics beneficial for treating autoimmune diseases
They alter the immune response so the body does not continue to attack itself
What would be needed in order to create a malaria vaccine
A weakened malaria parasite
What vector or type of cell is used to create recombinant insulin?
Bacteria
MoAb drugs can be used to treat what?
Cancer, anti-rejection medication in organ transplants, treatment of Crohns disease and diagnosis of various conditions
Cytokines are currently used to treat what?
Cancer and reduce the side effects of chemotherapy
What are cytokines used to treat?
Cancer and autoimmune diseases
What type of diseases do vaccines protect against
Viruses and a few bacteria
What is a benefit of the discovery of recombinant growth hormone?
We now have a treatment for certain growth disorders
They are produces from myelomas that are genetically modified to create hybridomas
What are cytokines
Signaling proteins naturally produced in the body by while blood cells
How do biological response modifiers impact the immune system?
What diseases have been entirely or significantly eradicated by vaccination
Small pox, Chicken pox