Bleeding & Coagulation!

LABS

100

This test measures the INTRINSIC and COMMON pathways of the coagulation cascade 

Partial Thromboplastin Time (PTT)

200

this test BEST measures factors VIII, IX, XI, and XII because it is NOT as sensitive to the common pathway as PT

(a)PTT

300

The BEST screening test for disseminated intravascular coagulation (DIC)

D-Dimer (elevated result) 

400

This test is used to follow the effects of warfarin (coumadin)

Prothrombin Time (PT) (via INR) ((PT/INR))

500

This is the followup study you order after a patient's labs reveal prolonged aPTT

Mixing Study

DIAGNOSIS

100

a disease that requires diagnosis by exclusion 

immune thrombocytic purpura 

200

this condition causes elevated PT AND PTT (it's a severe case) with NORMAL bleeding time 

vitamin k deficiency

300

this disease demonstrates elevated PT in early disease, elevated PT and PTT in late disease, and low FGN in really late disease

liver disease

400

both of these diseases typically present with normal PT and normal PTT 

thrombotic thyombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS) 

500

these three labs are DECREASED in a patient presenting with DIC

PT, PTT, platelets 

Random Info From Class Yesterday

100

the most common inherited bleeding disorder

von Willebrand's Disease

200

this type of bleeding disorder is QUANTITATIVE 

(1 or 2)

type I

300

this test (answer 1) is very sensitive to the factor with the shortest half life (answer 2)

PT, Factor VII

400

the rareness of spontaneous bleeding in von willebrand disease is a way to differentiate it from this other condition 

hemophilia 

500

these two subtypes of von willebrand disease are autosomal RECESSIVE

Type 2N, Type 3