These two sites store white blood cells until inflammation begins
Bone marrow
Lymph system
The presence of this electrolyte is needed throughout the clotting cascade
Calcium
This commonly digested nutrient is critical to production of hemoglobin
Iron
Normal ranges for hemoglobin and hematocrit
14-15
40-45%
The exposure of this element triggers the extrinsic clotting cascade
Tissue factor
This is the first step of the inflammatory response according to Guyton
Vasodilation of site
Liver
The body will make this many platelets per day per ml of blood under normal circumstances
30,000
This volume of blood is what contains all of the clotting factors
Plasma
This is the most prevalent circulating clotting factor
Fibrinogen
White blood cells have these two roles addressing invading pathogens
Phagocytic ingestion
Antibody formation
This factor is involved in both the extrinsic and intrinsic pathway
Factor X or Xa
The life span of RBCs
120 days
This waste product of warming fresh frozen plasma is used as another blood product
Cryprecipitate (Fribrinogen)
This common laboratory test evaluates Factors VII, X, and V
Prothrombin Time
This system intercepts soft tissue interstitial space pathogens and prevents insertion into blood
Lymphatic system
This circulating in blood binds to platelets at the vascular injury sites by Glycoprotein IIb
von Willebrand Factor
This hormone, primarily excreted by the kidney, initiates the production of RBC
Erythtropoietin
The product Kcentra contains these 4 factors
II, VII, IX, X
Heparin works on this naturally circulating plasma protein, increasing its action by 1000 times
Anti-thrombin III
Neutrophils comprise this percentage of white blood cells
60%
Thrombin has these three important roles in the clotting process
Form clot
Activate platelets
Catalyze formation of fibrin
Thromboxane A2
This enzyme contained in RBCs changes CO2 and water to carbonic acid and eventually bicarb to be transported in the plasma
Carbonic anhydrase
This mechanism results in thrombin generating more thrombin and more fibrin being enmeshed until hemorrhage ceases
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