i
A person whose red cells type as M+N+ with antisera would be termed as:
Heterozygous
Homozygous
Linked
Undeterminable
Heterozygous
What process is described by opsonization?
a. Lysis of cells
b. Binding to cells or antigens to promote phagocytosis
c. Ingestion of cells
d. Phagocytosis
Binding to cells or antigens to promote phagocytosis
What is the test procedure that combines patient’s serum or plasma with commercial A1 and B reagent red cells?
reverse type
System associated with paroxysmal cold hemoglobinuria (PCH)
Auto Anti-P
A 58-year-old man has a hemoglobin level of 5.9 g/dL. White blood cell and platelet counts are within normal levels. The patient is group B, D-negative with a negative antibody screen. Crossmatches are compatible. However, 15 minutes after the start of the first transfusion, he experiences erythema, itching and hives. What type of transfusion reaction is likely occurring?
Uticarial
Delayed hemolytic
TRALI
TACO
Febrile
Acute hemolytic
Uticarial
Given the following ABO phenotyping data:
FORWARD Anti-A: 2+mf, Anti-B: 0
A1 cells: 0, B cells: 3+
What could be a plausible explanation for this discrepancy?
A patient given O blood
Which of the following components in the complement cascade mediates the lysis of the target cells?
a. C1qrs
b. C4a, C3a, and C5a
c. C5 to C9
d. C3a and C3b
c. C5 to C9
Which tests are performed to identify the cause of suspected hemolytic disease of the fetus and newborn?
ABO, Rh, DAT, or all of the above
All of the above
System associated with resistance to malaria
Duffy
What is the cause of posttransfusion purpura?
Platelet antibodies
Which of the following organizations are involved in the regulation of blood banks?
FDA
JC
CAP
CLIA
FDA
What biological molecules are considered the most immunogenic?
Enter option 1 in plain text
Carbohydrates
Lipids
Enzymes
Proteins
Proteins
When is the immediate-spin (IS) crossmatch an acceptable procedure for the recipient?
When they don't have a clinically significant antibody today or ever!
Which condition is often associated with the presence of anti-I?
Mycoplasma pneumoniae
Which of the following conditions can result from long-term red blood cell transfusions?
Hemosiderosis
Red cells that phenotype as S–s– are also:
M-negative
U-negative
N-negative
K-negative
U-negative
How long following transfusion must the recipient’s sample be stored?
In an antibody identification panel, two red cells were positive at the antihuman globulin phase. The Autocontrol was negative. On ruling out and matching the pattern, an anti-C was identified. What further testing is necessary to confirm the antibody?
Confirm at least two red cells on the panel are negative for C and antigen type patient for the C antigen as long as patient has not been transfused in past 120 days.
What is the immunoglobulin class of most Rh system antibodies?
IgG
What antibodies cause an anaphylactic transfusion reaction?
IgA, IgG, IgM, or IgE
IgA
Describe the principle for the Kleihauer-Betke test and why do we do it?
Fetal hemoglobin is resistant to acid elution and remains in the cell to stain pink, whereas adult cells appear as ghost cells.
We do the test to quantify how much fetal blood made it into mom's blood stream so we can calculate how much rhogam she needs to protect her from making Anti-D
What temperature is used for incubation in the indirect antihuman globulin test?
37 degrees C
The rosette test will detect a fetomaternal hemorrhage as small as _______ml.
10mL
Which of the following red cell antigens do proteolytic enzymes destroy?
Duffy
A patient’s antibody history listed an anti-Cellano. This antigen was previously known as:
Kell