Week 13:
Coated vesicle trafficking from the endosomes to the Golgi apparatus.
What is a retromer?
This translocator in the ER helps phospholipids move rapidly between the two leaflets of the lipid bilayer
What is scramblase?
This type of vesicle buds from the trans-Golgi network to transport new lysosomal enzymes after they've been tagged with Mannose-6-phosphate.
What is clathrin-coated vesicle?
What membrane-bound cellular compartment accounts for the majority of the cell volume?
What is the cytosol (54%)?
Adaptor protein that selects the cargo of Clathrin coated vesicle.
What is AP2?
These proteins in the cytosol carry individual lipid molecules from the ER to mitochondria and plastids
What are lipid transfer proteins?
This GTP-binding protein acts like a molecular postal code during vesicle transport. It makes sure that vesicles dock with the correct target membrane.
What are Rab proteins?
The process by which a protein usually unfolds to snake through a translocator. ER lumen, ER membrane, and mitochondria entry all occur this way.
What is protein translocation?
This forms the outer layer of the COPII-coated vesicle.
What is Sec13/31?
Two of the oxidative enzymes contained in peroxisomes
What are catalase and urate oxidase?
This adaptor protein binds cargo receptors and clathrin, linking membrane-bound cargo to the forming vesicle during vesicle formation.
What is adaptor protein 2?
What organelle has the scaffolding component of pre-rRNA that recruits other proteins and snoRNAs?
What is the Nucleolus?
It fuses membranes to facilitate unload of the vesicle cargo
What are SNARE proteins?
This is required for the import of nearly all nucleus-encoded mitochondrial proteins
What is a TOM complex?
This is a process that involves enzymes in the Golgi adding sugars to the amide nitrogen of an asparagine residue on a protein.
What is N-linked glycosylation?
What protein triggers GTP hydrolysis converting Ran-GTP to Ran-GDP?
What is GTPase-activating protein?
Retrieval sorting signal with two lysine amino acids in the ER membrane C terminal
What is the KKXX sequence?
All of the following structures are part of the nuclear compartment except: Nuclear envelope, Nuclear Lamina, Nuclear Pores, Nucleoplasm, Nucleolus, Nuclear Centrioles
What are nuclear centrioles?
Secretory vesicles do not immediately fuse with the plasma membrane after docking. Fusion is triggered when this signal is present.
What is a rise in intracellular Ca2+?
This protein is a cytosol-facing membrane protein anchored in the membrane by a single transmembrane alpha helix very close to the C-terminus.
What is a tail-anchored protein?