Neuro
Drugs
Therapy
Neurobiology
Random
100
Absence seizure disorder is characterized by which of the following findings? a. Onset of seizures in young adults b. Slow (less than 3 Hz) spike and wave discharges on EEG c. Seizure spells extremely refractive to medical tx d. Normal mentation e. Spontaneous remission of seizures rare
What is b. Slow (less than 3 Hz) spike and wave discharges on EEG
100
Based on having the longest half-life which of the following benzos is most likely to caused increased daytime sedation and non-alertness? a. Estazolam b. Flurazepam c. Oxazepam d. Temazepam e. Triazolam
What is B. Flurazepam (100)
100
Which one of the following organizations is an established grassroots self-help and advocacy organization in the US for individuals with mental illness and their families? a. American Psychiatric Association b. National Institute of Mental Health c. National Alliance on Mental Illness d. National Council for Behavioral Healthcare e. Centers for Medicare and Medicaid Services
What is c. NAMI
100
Disturbance in which one of the following neurotransmitter systems is implicated in seasonal affective disorder? a. Cholinergic b. Dopaminergic c. Glutaminergic d. Noradrenergic e. Serotonergic
What is E. Serotonergic
100
What statement is true regarding AA? a. Each major city has a chapter of AA that directly reports to global headquarters b. It is official AA policy to recommend that all members discontinue psychotropics c. Even after a year, if you don't believe in God, you must leave AA d. The only requirement for AA membership is a desire to stop drinking e. AA operations are partially funded by the gov't
What is D
200
72yo M with a neurocognitive d/o develops frightening VH. Low dose risperidone is given and pt develops severe bradykinesia, tremor, rigidity and gait disturbance. His a/e suggests what diagnosis? a. NCD due to Alzheimer's disease b. NCD due to Lewy body disease c. Normal pressure hydrocephalus d. Progressive supranuclear palsy e. NCD due to vascular disease
What is B. NCD due to Lewy Body disease
200
Which of the following is true of all FDA approved hypnotic agents? a. They have a high abuse potential b. They are restricted by the FDA for short-term use c. They are FDA approved for sleep maintenance d. They exert their effects through the GABAergic neurotransmitter system e. They are FDA approved for sleep initiation
What is E. they are FDA approved for sleep initiation
200
Treatment of factitious disorder imposed on self should initially focus on which one of the following goals? a. Discussion with family members to engage in family therapy to help manage symptoms b. Symptom management while avoiding needless medical procedures c. Confrontation of the patient regarding the disorder and his/her role in it d. Hypnosis to delineate underlying issues e. Discontinuation of all tx by PCP, as this only reinforces the maladaptive behavior
What is b. sx management
200
Which one of the following statements regarding CNS maturation is true? a. Visual perception is well-developed at birth b. Fetus can hear sounds in utero c. Synapses are completely developed by 6 months of age d. Infants cannot recognize mother's voice until 1 year of age e. Social smile develops by first week
What is b. fetus can hear
200
Children and adolescents acquire AIDS most commonly how? a. IV drug use b. Homosexual activity with an HIV-infected person c. Heterosexual activity with an HIV-infected person d. being born to a mother with HIV e. Transmission through saliva
What is D.
300
A 70yo M presents with memory loss. Spouse reports increasing forgetfulness, inattention and significant short-term memory loss. She also reports pt has been having hallucinations of seeing unfamiliar people in his house and yard. Patient recognizes these are not real and is not troubled by them. Pt also has mild L hand resting tremor and slightly increased L arm tone. What is the dx? a. Parkinson's disease b. Schizophrenia c. Parkinsonism secondary to manganese exposure d. Multiple system atrophy e. Lewy body disease
What is E. Lewy body disease
300
A 17yo F asks specific questions about AEDs, such as their impact on school, health and pregnancy. What response is best? a. Folic acid during pregnancy may decrease the risk of neural tube defects due to AED use b. The risk of teratogenicity is solely due to AED use c. Phenytoin has no impact on bone density d. AEDs have their greatest negative impact during the 3rd trimester e. Cognitive impairment is an uncommon side effect of AEDs
What is a. Folic acid
300
Which one of the following statements regarding system family therapy approach is true? a. Views symptoms as serving a purpose for the family b. Places emphasis on the psychopathology of the child c. Places emphasis on psychodynamic mechanisms d. Uses exposure and response prevention to resolve complexes e. Places emphasis on the psychopathology of the parents
What is a. sx serve a purpose for the family
300
A 30yo M being treated for depression presents with lethergy, confusion, diaphoresis, flushing, tremors and myoclonic jerks. Which of the following diagnoses is most likely? a. Anticholinergic delirium b. Serotonin syndrome c. SSRI withdrawal d. Neuroleptic malignant syndrome E. Delirium tremens
What is B. serontonin syndrome
300
The 2 peaks of onset of illness in panic disorder occur at what ages? a. Mid 30s and mid 60s b. Preschool and late adolescence c. Late adolescence and mid 30s d. Preschool and mid 60s e. Late adolescence and mid 60s
What is C
400
61yo M with HTN and HLD presents with 45min episode of difficulty speaking, twisting of his face, R arm weakness which has since resolved. He is admitted for w/u of a TIA. Echo is negative for cardiac emboli. Carotid u/s shows no significant stenosis. MRA shows diffuse intracranial atherosclerotic disease. What therapy is most appropriate? a. IV heparin b. Clopidogrel c. Folic acid d. Aspirin e. IV TPA
What is D. Aspirin
400
Adding which of the following SSRIs to a patient's medication regimen is most likely to raise serum levels of theophylline and haloperidol? a. Citalopram b. Escitalopram c. Fluoxetine d. Fluvoxamine e. Sertraline
What is D. Fluvoxamine (inhibitor and substrate for CYP1A2)
400
Which one of the following approaches to the tx of illness anxiety disorder is taken from the perspective of amplification theory? a. Relaxation exercises to distract pt from perceived physical sx b. Confront the patient about lack of a true illness c. Work with the pt to re-conceptualize the symptom as a natural event d. Address past relationships with an eye toward issues of guilt e. Prescribe an anxiolytic
What is C. re-conceptualize
400
Stiff person syndrome is often associated with which one of the following types of antibodies? a. Anti-glutamic acid decarboxylase (GAD) antibodies b. ANNA-1 (anti-Hu) antibodies c. Antibodies directed against presynaptic voltage-gated P/Q type calcium channels d. Asialo-GM 1 antibodies e. MAG (myelin-associated glycoprotein antibodes)
What is A. GAD antibodies
400
Tranylcypromine is a medication from what class? a. Low potency neuroleptics b. Monoamine oxidase inhibitors c. Opioids d. SNRI e. TCA
What is B. MAOI
500
58 yo W w/ HTN complains of double vision. Ophtho exam was WNL except for no adduction past the midline of the R eye and abducting nystagmus of the L eye. Exam 2 months later showed ptosis bilaterally, no adduction and nystagmus on abduction of the R eye, and limited adduction, abduction and elevation of the L eye. The rest of the neuro exam is WNL. What is the etiology? a. Multiple sclerosis b. Brainstem infarction c. Brainstem tumor d. Myasthenia gravis e. Thyroid orbitopathy (graves' disease)
What is d. myasthenia gravis
500
Ingestion of which one of the following available common foodstuffs or herbal preparations is capable of producing symptoms resembling LSD intoxication? a. Rosemary b. Nutmeg c. Morning glory seeds d. Betel nuts e. Ephedra
What is c. morning glory seeds
500
Which one of the following psychotherapies is a manual-based psychotherapy whose focus is limited to the following aspects of a patient's functioning: the conflicts, role transitions, grief, and deficits that contribute to a depressive disorder? a. Depressive disorders psychotherapy b. Dialectical behavioral therapy c. Interpersonal therapy d. Object relations therapy e. Psychosocial rehabilitation
What is C. IPT
500
Which one of the following TCAs has lower anticholinergic activity than the others? a. Amitriptyline b. Clomipramine c. Doxepin d. Imipramine e. Nortriptyline
What is E. nortriptyline
500
Which one of the following depressive symptoms specifies depression with melancholic features? a. Depressed mood b. Depression worse in the evening c. Difficulty falling asleep d. Leaden paralysis e. Early morning awakening
What is E.early morning awakening