BOC Prep Round 1

Immunostains

100

Immunostain used to confirm lung primary

TTF-1

200

Immunostains chromogranin and synaptophysin are positive. These findings indicate what type of tumor?

Neuroendocrine

300

A positive result for this immunostain is diagnostic of a GIST

DOG-1

400

Immunostain used to indicate breast primary

GATA-3

500

FNA of an abdominal mass shows malignant cells that stain positive for PAX-8. The tumor primary is most likely what?

Kidney / Renal cell carcinoma

Processing/Techniques

100

A milky appearance in the presence of an otherwise fine stain quality would suggest what preparatory issue? 

Water in xylene

200

The alcohol steps used in the pap stain process are for what purpose?

Allow transparency through cells 

300

What is the purpose of xylene in the staining setup?

Clearing agent

400

What solution can be used to dissolve a ferruginous body?

Bleach

500

What is the artifact in which air pockets are trapped under the coverslip causing brownish spots that preclude viewing of the cells underneath?

Cornflaking

GYN

100

The strain of HPV most commonly associated with endocervical adenocarcinoma is...

HPV 18

200

What is the most common processing error on vulvar scrapings?

Air-drying

300

Patient is a 29 y.o. female. According to ASCCP guidelines, what is the recommended follow-up for a cytology result of ASCUS and a negative HR-HPV test?

Repeat co-testing in 3 years

400

Patient is a 24 y.o. female, 1 week post-partum. Assuming for a normal maturation index, what is the predominant cell type present on her pap test?

Parabasal

500

The most likely reason for glandular cells appearing on a vaginal pap sample is what?

Vaginal adenosis

Non-GYN

100

Multiple nodules occurring is more common in primary disease or metastatic disease?

Metastatic

200

Compared to other types of lung cancer, this type tends to occur more peripherally within the lung.

Adenocarcinoma

300

Most malignancies occurring in the renal pelvis tend to be what type?

High grade urothelial carcinoma

400

Voided urine of a 60 y.o. male with a hx of TCC shows scattered large polygonal cells, some of which are multi-nucleated. Nuclei are large nuclei with occasional atypia in the chromatin. What is the most likely diagnosis?

NHGUC

500

What is the most common malignancy that occurs in the liver?

Metastatic disease

Lab Operations & Safety

100

What is the most common type of fire extinguisher found in the lab?

ABC

200

What is the most effective universal precaution to take in the lab to prevent the spread of infection and contamination?

Hand washing 

or

PPE

300

What often must a cytotechnologist perform proficiency testing to maintain certification?

Annually

400

A cytotechnologist with 5 years experience has a daily quota set at 80 slides.  They are now using the ThinPrep Imager Review Scope and screen 120 slides, 20 of which a full manual review was performed over an 8 hour timeframe. Did this cytotechnologist stay within screening limit guidelines?

Yes

500

What is the proper order to don and doff PPE including eyewear, gloves, and a labcoat?

Don - Coat, gloves, eyewear

Doff - Reverse