Organisms
Endometrial and Ovarian
Special Stains
Ancillary Testing
FNA
100

This fungal organism can be described as flat, wavy, non-septate, with varying widths of branching

Zygomyces

100

What hormone is responsible for ovulation

Luteinizing hormone

100

Special stain used for fungal organisms

GMS

100

70 y.o. male with trouble in urination presents with multiple bone lesions. Cytology reveals small round cells with granular cytoplasm and prominent nucleoli. What additional test can be used to confirm the diagnosis?

PSA test

100
A 30 y.o. female presents with a solid breast mass. Cytology reveals large sheets of closely cohesive small bland cells and a corresponding stromal component. What is the most likely diagnosis?

Fibroadenoma

200

Organism identified by the empty spaces and casts it leaves when stained by H&E or the pap stain

Pneumocystis

200

What is the most common sarcoma found in the uterus of post-menopausal females.

Leiomycosarcoma

200

Special stain used for amyloid in which the reaction is observed under a refractile polarizing microscope

Congo Red

200

What fixative should be used for what testing platform when lymphoma/leukemia are considered differentials?

RPMI - Flow Cytometry

200

What is the distinguishing feature used to differentiate Hodgkin Lymphoma from other hematopoietic conditions? 

Reed-Sternberg cells

300

Organism associated with gastric ulcers in up to 90% of cases

H. Pylori

300

Which is most likely to be true in a grade 1 endometrial carcinoma?

- Tumor in minimally invasive

- Malignancy has not spread outside of the uterus

- Histologically, the tumor is considered well-differentiated

Well-diff

300

Special stain for mycobacterium when questioning TB

AFB

300

How many copies of a gene are present if the FISH result is tetrasomy?

4

300

Thyroid FNA sample shows abundant lymphocytes, rare follicular cells, scattered hurthle cells, and limited colloid. The most likely diagnosis is what?

Hashimoto's thyroiditis

400
This organism commonly causes a granulomatous response and is characterized by a thin refractile wall around the nucleus.

Blastomyces

400

This tumor occurs in elderly women and may be heterogeneous or homogenous in it's makeup. The heterogeneous version would include an epithelial variant, commonly adenocarcinoma, and a sarcomatoid component.

MMMT

400

Special stain commonly used to identify pigment in pulmonary macrophages

Prussian blue

400

PCR and nucleic acid hybridization are used in HPV testing for _____________ of the target DNA.

Amplification

400

Lymph node sampling shows abundant polymorphic lymphocytes and tingible body macrophages. The most likely diagnosis is what?

Benign, reactive lymph node

500

A sputum sample reveals structures forming acute-angle branching of pseudo-hyphae and small eosinophilic spores. Why would this not be a reportable finding?

Candida is normal flora from the oral cavity and a contaminant in sputum samples

500

35 y.o. female currently cycling shows ball-like groupings of tightly cohesive small round cells with hyperchromatic nuclei. What are these cells secreting?

Glycogen

500

Special stain used for a variety of reasons including to stain glycogen, mucin, and certain types of fungi

PAS

500

Physical exam and FNA/Biopsy are two the "big 3" exams to consider in breast pathology. What is the third?

Mammogram

500

A 4 y.o. seen prior for a retroperitoneal and renal mass and ascites fluid now presents with a brain mass. Cytology reveals small round blue cells with limited cytoplasm. What is the most likely diagnosis?

Nephroblastoma