Inflammatory disorders
Benign lesions
Breast Carcinoma
Miscellaneous
Staging
100

This bacterium can cause a local infection of the nipple when breastfeeding.

Staphylococcus aureus

100

What is the most common benign tumor of the female breast?

Fibroadenoma 

100

What are the three molecular classifications of breast carcinomas?

Luminal, HER2-enriched, and Basal-like

100

T or F: The risk of malignancy with discharge increases with age?

True 

100

Tumor staging for breast carcinoma is based on what? 

Size of tumor 

200

What lesion is also called a subareolar mass or periductal mastitis?

Squamous metaplasia of lactiferous ducts

200

In what scenario is adenosis normal in the breast?

It is normal in pregnancy 

200

Which carcinoma is associated with the loss of E-cadherin?

Lobular carcinoma in situ 

200

Which lesion has a MED12 mutation and is characterized as having leaf life projections?

Phyllodes tumor 

200

A patient has a tumor that is 6mm in greatest dimension. What is the stage? 

T1b

300

What is the treatment for granulomatous mastitis?

antibiotics or sometimes steroids 

300

Which benign lesions have components of adenosis, papilloma, and epithelial hyperplasia?

Complex sclerosing lesion 

300

Which mutation is more closely associated with Male breast carcinoma?

BRCA2

300

Which tumor is most likely to arise in association with breast implants?

T-cell lymphoma 

300

A patient has an invasive breast tumor measuring 3.5 cm with involvement of the chest wall. What is the T stage? 

T4

400

The name of a palpable periareolar mass often associated with thick white nipple secretions seen in the 5th or 6th decade of multiparous women 

Duct ectasia 

400

These two histological findings are classic components of fibrocystic changes and can produce a palpable breast mass.

Cyst and fibrosis 

400

What is the most common site of breast carcinomas?

Upper outer quadrant 

400

What cell types make up the ducts and lobules of the breast?

luminal epithelial cells and myoepitheial cells

400

What is the requirement for a T3 stage?

Tumor >50 mm in greatest dimension

500

This benign stromal mass can be mistaken for carcinoma because it produces a firm, irregular mass following trauma. What is the lesion?

Fat necrosis

500

This benign breast lesion is characterized by fibrovascular cores histologically and commonly presents with spontaneous bloody nipple discharge.

Intraductal papilloma 

500

Once malignant ductal cells invade through the basement membrane into the surrounding stroma, the diagnosis changes from what to what? 

Ductal carcinoma in situ to invasive ductal carcinoma 

500

A 40-year-old is seen for a mass in the stroma of the breast as a complication of the radiation therapy she received 5 years ago. What is the most likely diagnosis?

Angiosarcoma 

500

A breast tumor measures 4.5 cm without chest-wall or skin involvement. What is the correct stage for this tumor? 

T2