Experimental
light color that activates Halorhodopsins
yellow
Full name of MRI
Magnetic Resonance Imaging
Full name of PET
positron emission tomography
meaning of "in vivo"
"within the living" taking place within a living organism
the target for immunohistochemistry
proteins/antigens
benefit of optogenetics over electrical stimulation
can stimulate individual neurons
500-570 nm
cause of safety risks for PET/CT
radiation exposure, allergic reactions to contrast/tracer
2 methods to assess region/circuit function
EEG, EMG, PET, Fiber Photometry, Microscopy, RNA/Protein methods
source of the GFP gene
bioluminescent jellyfish
an interaction a drug can have with its target
the drug binds to an active site on an enzyme, the drug interacts with the cell surface signaling proteins, the drugs that act by binding molecules
how is Dlight created
replacing a portion of the dopamine receptor with a GFP molecule which responds to light when activated by dopamine
advantage of a CT scan
less time consuming and less expensive
The capacity a technique has to tell you when the activation happened
temporal resolution
number of Brodmann areas
52
Deep brain stimulation has potential to treat...
OCD, Depression
how big is a micron relative to a millimeter
1 mm= 1000 microns
term for regions with little recorded metabolic activity in PET scan
imaging technique that can detect cancer first
PET
2 methods that require surgery
Deep brain Stimulation, fiber photometry
when a drug behaves as neither and antagonist or agonist
stabilizing action
Vibrational resonance from the magnetic field switching on and off
what shows up black, gray, and white on a CT
dark/black=air, water, or fat gray=soft tissue (muscle) white=dense tissue (bone)
A limitation of fluorescence microscopy
prone to photobleaching, too much or little emitted light
virus that can be used to follow a circuit in the retrograde direction
Rabies (labelled)