Figure 1
This is the effect that the mutations BRCA1-flex2/flex2, p53, and WAP-cre/+ have on tumor-free survival rates.
What is decreased survival rates?
This mutation prevents an interaction between BRCA1 and BACH1.
What is theS1598F mutation?
These types of mice survived the induced breast cancer.
What are S1598F mutated mice and null mutated mice?
The Kras mutation involves this type of cancer.
What is pancreatic cancer
Pancreatic tumor development is suppressed by this type of mutant.
What is a triple-mutant?
Cells with a mutant BRCA1 are deficient in this important cellular function.
What is DNA repair?
These mutations have similar survival curves.
What are the S1598F and Tr mutations?
The Flex2 mutation is associated with this gene.
What is BRCA1?
The type of graph used to estimate survival function is called this.
What is a Kaplan-Meier Survival Curve?
This type of mouse had a 68.1% greater chance of developing a tumor when compared to the control group.
What is a homozygous S1598F/S1598F mouse?
This mutation dramatically reduced survival time.
What is the Kras mutation?
This is the biggest difference between the wildtype mice, and the mice with the I26 mutation.
What is smaller testes and sterility?