The phase I metabolism reactions of salbutamol?
What is esterification and oxidative deamination
The time frame at which salbutamol takes to produce an effect
What is quick, short acting
This is what salbutamol is used to treat.
What is asthma?
We found that this parameter had no correlation to the activity of bronchodilators.
What is logP?
What is Airomir , Combivent, Proair, Proventil, Ventolin, or Xopenex?
What is a t-butyl group?
The R-isomer of salbutamol causes
What is bronchodilation
The location of metabolism of salbutamol?
What is the liver
The difference between epinephrine and salbutamol is that epinephrine has this bound to the nitrogen.
The gender most common to have childhood asthma?
What are boys
The pharmacophore of salbutamol had this number of hydroxy groups.
What is 2?
The phase II metabolism of salbutamol?
What is conjugation with glucuronie
This bronchodilator showed significantly longer duration of action than salbutamol.
What is formoterol?
The different derivatives of the bronchodilators varied depending on what is bound to this atom.
What is nitrogen (amine)?
Salbutamol is very similar in structure to this natrually produced hormone.
What is epinephrine?
The enantiomer with higher concentration in plasma?
What is (S)-salbutamol
The selective receptor of salbutamol?
What ion is elevated by (S)-salbutamol?
What is Ca2+
The three effects of asthma on the airways
What is inflammation of the smooth muscle, swollen lining, and excess mucus build up
Which enantiomer has faster elimination?
What is (R)-salbutamol