PHARM
ACS
CVA
DM
WILD
100
Brilinta is a platelet inhibitor
What is P2Y12?
100
Three categories of ACS
What are STEMI, NSTEMI, and UAP?
100
Fifth leading cause of death and leading cause of disability
What is stroke?
100
Heart disease equivalent
What is diabetes mellitus?
100
Karen Jenkins maiden name
What is Jolly?
200
Brilinta has a loading dose
What is 180 mg?
200
Three treatment strategies for ACS
What are OMT, PCI, and CABG?
200
Stroke identification
What is FAST?
Facial droop, Arm weakness, Speech difficulty, and Time to call EMS
200
Test result neutralizes heart disease equivalence of diabetes
What is CAC score of ZERO?
200
Karen Jenkins favorite provider
Who is Don Chomsky?
300
Brilinta achieves steady state platelet inhibition following a loading dose
What is 2 hours?
300
Standard anti platelet regimen following PCI
What is DAPT?
300
3 endovascular devices for stroke prevention
What are carotid stents, LAA occluders, and PFO occluders?
300
Cardiovascular event reduction in diabetics
What are SGLT-2 inhibitors?
300
Brilinta mono therapy
What is TWILIGHT (NEJM 2019)?
Ticagrelor with or without Aspirin in High-Risk Patients after PCI
44% reduction in bleeding with no difference in ischemic events
400
Brilinta achieves a percentage of platelet inhibition
What is 80%
400
Anti platelet regimen that reduces cardiovascular mortality following ACS
What is Brilinta and low dose aspirin?
400
Study evaluated DAPT vs aspirin for CVA
What is Thales (NEJM 2020)?
A 20% reduction in stroke and death with Brilinta and aspirin compared to aspirin mono therapy.
400
Study evaluated diabetic patients at risk
What is Themis: Ticagrelor in Patients with Stable Coronary Disease and Diabetes (NEJM 2019)?
10% reduction in cardiovascular events
400
Cost of Brilinta
Free
500
Hold Brilinta prior to a major surgery
What is 5-7 days?
500
Long term dose of Brilinta was evaluated
What is Pegasus TIMI-54 (NEJM 2015)?
Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction: 60 mg twice daily in combination with low dose aspirin reduced subsequent events by 16%
500
Brilinta better than clopidogrel for CVA for subgroups
CHANCE-2 (NEJM 2021): Ticagrelor versus Clopidogrel in CYP2C19 Loss-of-Function Carriers with Stroke or TIA
23% reduction of recurrent stroke
500
Diabetic bleeding complications
What was bleeding in Themis?
More bleeding with Brilinta but fatal bleeds were comparable.
500
Brilinta trials have enrolled a number of patients
What is > 110k patients?