NGS
Next Generation Sequencing
Name one barrier why NSCLC patients may not receive adequate biomarker testing.
What is: not enough tissue to run the test, or patient is to sick for a biopsy, cost/reimbursement of the test, test wasn't ordered,
Name 3 predictive biomarkers in breast cancer that leads to targeted therapy?
Hormone receptor positive (ER/PR)
HER2+
Triple Negagive
What is 27 Biomarker Specialist
What does NSCD stand for?
What is:National Supply and Care Delivery
MDT
Multi-Disciplinary Team
Name 2 biomarkers that NCCN recommends testing in NSCLC patients.
ALK, ROS1, EGFR, RET, MET, BRAF, HER2, NTRK, PDl1
What time period would a lab be concerned if the breast tissue does not reach their lab for testing?
less than 1 hour
Who are the 3 AD's on the Biomarker Testing Team
Michele Wilson
Timoli Matthews
Mike Beauchamp
Name one of the 1 operating principles than is important to NSCD.
What is: 1.I radically simplify and prioritize for impact
2. I build a culture of trust.
3. I act on behalf of the whole company not just my team.
PHC
Personalized Healthcare
Approximately what % of patients have oncogenic driver mutations in NSCLC
approximately 64%
What guidelines are followed by the breast MDT for all aspects of ER/PR & HER2 testing?
What is: ASCO/CAP
What was the original name for BTT in 2012?
PREP (Program for Reaching and Educating Pathologist)
Name the 5 nWOW pilars (TTPFF )
Trust, Transparency, Push, Focus, & Flow
IHC
ImmunoHisto chemistry
Stage IV lung cancer patients have a median untreated life expectancy of approximately how many weeks?
approximately 16 weeks
What is the prevalence of patients that have HER2+ breast cancer?
What is: approximately 15%
Where can testing occur?
What is: Local hospital labs, regional reference labs a(Path Group, GenPath), national reference labs(LabCorp,Quest), speciality labs (Guardant, Tempus, FMI), Academic Center of Excellence Lab (Mayo, Hopkins, MSK, etc)
What is: 50%
F1CDx
Foundation One Companion Diagnosis
What is another testing option when lung tissue is not adequate or available?
Liquid biopsy
In mTNBC what percent is PDL1+ and what therapy is available to this patient population?
What is: approximately 41% and Tecentriq
Name 5 of BTT's external customers
What is: Pathologist, Oncologist, C-suite, Lab staff, lab manger, lab director, tissue collectors, tumor registrar, quality improvement managers, nurse navigators, precision medicine directors
What is Becky's favorite beverage?
Mountain Dew