bugs n drugs

bac

100

the link between Salmonella infection and
osteomyelitis in patients with sickle cell disease.

What is gut infarcts in pts with SCD result in leakage of gut microbes into the basal lamina, lymph and blood. Salmonella is exceptionally well suited for survival in the blood b/c it can survive within monocytes/macrophages. From the blood it is translocated to the bone. (also asplenia)?

200

 the etiology, epidemiology and pathophysiology of hemolytic uremic syndrome (HUS) in EHEC

Shiga toxin damages the endothelium, resulting inexposure of TF and initiation of clotting cascade,which leads to the formation microthrombi. As themicrothrombi circulate, they can cause mechanicaltrauma to RBCs as they pass through capillaries,leading to intravascular hemolysis and schistocyteformation.Clotting factors are consumed during the formationof microthrombiMicrothrombi damage renal endothelial cells andclog glomeruli compromising kidney function. Thisis a critical aspect of HUS, as it can lead to acutekidney injury.

300

gram (+) catalase negative non-hemolytic coccus

What is enterococcus?

400

G+, cat+, coag+ cocci

what is staph aureus?

500

Bacteria one should be owrried about with a CD4 count >50

MAC

vir

100

4 diseases caused by Herpesviridae family members

What are 

Herpes simplex 1 & 2
Epstein-Barr virus
Human cytomegalovirus
Varicella-zoster virus

HHV 6/7 = roseola infantum

HHV 8 = kaposi

200

Hep A virus group?

What is picornaviridae

300

influenza virus group

What is orthomyxoviridae

400

Positive markers for a recent, highly infections HBV

What are HBsAg, HBc IgM, HBeAg

500

Dengue virus virus group and genome type

What is (+) RNA Flaviviridae

misc

100

the etiology, prevention, and management of pressure injuries.

What are pressure injuries are caused by prolonged pressure, shear, friction, and moisture, leading to skin and tissue damage, particularly over bony prominences. Prevention involves regular repositioning, use of pressure-relieving devices, proper skin care, nutrition, and risk assessments. Management includes wound assessment, debridement, infection control, appropriate dressings, and pain management?

200

The MOA of oseltamavir

what is neuraminidase inhibitor?

300

the moa of baloxavir marboxil

What is an enzyme inhibitor targeting the influenza virus' cap-dependent endonuclease activity?

400

6 pathogens commonly tested for on a rapid RVP

What are influenza A & B, COVID-19, Entero/RV, Mycoplasma pneumoniae, chlamidophila pnemoniae, parainfluenzas, adenovirus, coronovirus, rsv?

500

Tenofovir's two main side effects

nephrotoxicity and bone mineral loss