Autonomically-Mediated Effects
Stimulation of the salivary glands by the parasympathetic nervous system elicits this effect.
What is increased salivary secretions?
primarily used as a beta and alpha 1 agonist in the treatment of anaphylaxis
What is Epinephrine?
This neurotransmitter is released by all preganglionic autonomic neurons.
What is acetylcholine?
These drugs mimic the effects of the parasympathetic nervous system.
What is a Muscarinic Agonists?
How many bones are in the adult human body?
TWO HUNDRED AND SIX BONES
Stimulation of cardiac muscle by the parasympathetic nervous system has this effect on heart rate.
What is a negative chronotropic effect (lowered heart rate)?
A direct sympathomimetic characterized by a rise in heart rate and little to no effect on blood pressure due to the contrasting effects of beta 2 and alpha 1 activation
What is Dobutamine?
Bethanechol activates these receptors to promote urination.
What are muscarinic receptors?
Muscarinic agonists make the pupil do this, while antagonists make it do the opposite.
What is constrict (miosis) for agonists and dilate (mydriasis) for antagonists?
Which adrenergic receptors activate the Gs protein?
B1, B2, B3
Stimulation of the smooth muscle of the lung's airways by the sympathetic nervous system elicits this effect.
What is bronchodilation?
The result of decreased diastolic blood pressure and mean arterial pressure often seen when using Isoproterenol
What is Reflex Tachycardia?
This enzyme breaks down acetylcholine in the synaptic cleft.
What is acetylcholinesterase?
This muscarinic antagonist is found in the plant Atropa belladonna (deadly nightshade).
What is atropine?
How many Wii remotes does the LSUHS medical student lounge currently have?
FIVE WHOLE WII REMOTES
Stimulation of the pupillary sphincter and ciliary muscle by the parasympathetic nervous system is used to achieve these ocular effects (2).
What are miosis (pupillary constriction) and accommodation?
The main activated receptor that directly causes an increase in diastolic blood pressure and mean arterial pressure when using dopamine
What are Alpha 1 receptors?
This reversible acetylcholinesterase inhibitor treats myasthenia gravis.
What is pyridostigmine?
Although part of the sympathetic system, sweat glands use this type of receptor.
What is muscarinic receptor?
Isoproterenol administration results in both an increase in systolic blood pressure (B1 adrenergic) and decrease in diastolic blood pressure (B2 adrenergic). How does this drug affect mean arterial pressure (MAP)?
Stimulation of the kidneys by the sympathetic nervous system stimulates the release of this protein.
What is renin?
Postoperative treatment for pheochromocytoma to prevent catecholamine induced hypertensive crisis
What is Phenoxybenzamine?
Overactivation of muscarinic receptors can lead to this deadly condition characterized by DUMBBELSS symptoms.
What is a cholinergic crisis?
This antimuscarinic drug is used to treat motion sickness.
Scopolamine
What is Dr. First's neurological condition (shared with us in class)?
Prosopagnosia (face blindness)