Pathognomonics
Philadelphia Chromosome
CML
This acute leukemia is more likely to occur in adults than children
AML
Name the three phases of CML
Chronic, accelerated, and blast crisis
Name the 3 "B Symptoms"
Fever, night sweats, weight loss
Overproduction of what is the classic finding in Multiple Myeloma?
Monoclonal Immunoglobin (M Protein technically is correct)
Auer Rods
AML
What is a physical exam symptom that would prompt ALL workup in child? (one of these 6 correct possible answers)
unexplained pallor
unexplained fеver
unexplained bleeding/bruising
bone pain
hepatosplenomegaly
Unexplained lуmрhаԁеոоpаthу
What is the cutoff for blasts to qualify for blast phase?
>20%
What is a common finding on chest x ray that is suspicious for Hodgkin's Lymphoma?
Mediastinal Mass
What is the classic finding on radiographs that is highly suspicious for multiple myeloma?
Lytic Lesions
Reed Sternberg
Hodgkin Lymphoma
What would be the sign on CBC that leukostasis is present?
WBC >100
What is the most common physical exam sign for CLL?
Painless lymphadenopathy
What stage of lymphoma has positive cervical and inguinal lymph nodes, but no mets?
Stage 3
In the Acronym "OLD-CRAB" for the features of MM, what does "R" stand for?
Renal Failure
Bence Jones Proteinuria
Plasma Cell/Multiple Myeloma
Every patient with ALL requires this procedure due to its high rate of CNS involvement
Lumbar Puncture
What is seen on peripheral smear for CLL?
Smudge cells -or- Small mature lymphocytes and absolute lymphocytosis
Which lymphoma is associated with +EBV history
Burkitt
For MGUS to be diagnosed, there has to be less than what percentage of clonal plasma cells?
<10%
Painful Lymph Node after alcohol
Hodgkins
This is a specific marker expressed in ALL on immature lymphoblasts that confirms your diagnosis
(TdT) Terminal deoxynucleotidyl transferase
What is the name of the first line chemotherapy for CML?
Imatinib mesylate (Gleevec)
What is the acronym for first line chemotherapy with Hodgkin Lymphoma?
ABVD (Adriamycin, Bleomycin, Vinblastine, Dacarbazine)
Positive Congo Red Stain is associated with what disease?
Systemic Light Chain Amyloidosis