DNA
What's a carcinogen?
Something that is proven to cause cancer
G0 (optional)
G1
G2
S
M
What is a tumor
A tumor is an abnormal mass of tissue that forms when cells grow and divide more than they should or do not die when they should.
Why is it important to target the hallmarks of Cancer?
You can target the tumor and not the healthy cells.
What is DNA damage?
Anything structurally abnormal in DNA.
How likely is it for a woman to get cancer?
1 in 3 women get cancer in their lifetime
How many checkpoints are in the cell cycle?
There are 3 checkpoints.
About how many types of Cancer are there
More than 100 types of Cancer?
What are hallmarks of Cancer?
Hallmarks of Cancer are acquired functional capabilities that allow the Cancer cell to survive.
How many nucleotides are there in DNA?
4
What is a group one carcinogen?
Which phases of the cell cycle are included in interphase?
G1 G2 S
What is apoptosis?
programmed cell death
What is angiogenesis?
The creation of new blood pathways or vessels.
What does cytosine pair with in DNA?
Guanine
What is a group 4 carcinogen?
A group 4 carcinogen is something that is probably not carcinogenic
Why do cells go into G0
When they need to differentiate or lack of resources.
What is a biopsy?
A biopsy is removing a small piece of a tumor to determine its characteristics.
What is metastasis? What impact does it make
When harmful cancer spreads to other parts of the body. This is when it becomes lethal because it can cause a tumor in important organs of the body.
Give an example of a tumor suppressor gene?
TP53 is a tumor suppressor gene that controls cell growth and division.
What is a group 3 carcinogen?
It means that the carcinogenicity isn't classifiable and there is inadequate evidence in both humans and animals.
What happens at the second checkpoint in the cell cycle?
If the DNA replicated fully and precisely.
What is a prognosis?
A prognosis is something that describes your chance of recovery after treatment and life outcomes.
What is uncontrolled proliferation?